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18 2", "upper_bound": 1000.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["CEPTE_16_0_18_2"]}, "metabolites": {"cdpea_c": -1.0, "dag_hs_16_0_18_2_c": -1.0, "h_c": 1.0, "pe_hs_16_0_18_2_c": 1.0, "cmp_c": 1.0}, "id": "CEPTE_16_0_18_2", "gene_reaction_rule": "CEPT1"}, {"subsystem": "Glycerophospholipid Metabolism", "name": "CEPTE 18 1 18 1", "upper_bound": 1000.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["CEPTE_18_1_18_1"]}, "metabolites": {"pe_hs_18_1_18_1_c": 1.0, "dag_hs_18_1_18_1_c": -1.0, "cdpea_c": -1.0, "h_c": 1.0, "cmp_c": 1.0}, "id": "CEPTE_18_1_18_1", "gene_reaction_rule": "CEPT1"}, {"subsystem": "Glycerophospholipid Metabolism", "name": "CEPTE 18 1 18 2", "upper_bound": 1000.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["CEPTE_18_1_18_2"]}, "metabolites": {"cdpea_c": -1.0, "pe_hs_18_1_18_2_c": 1.0, "dag_hs_18_1_18_2_c": -1.0, "h_c": 1.0, "cmp_c": 1.0}, "id": "CEPTE_18_1_18_2", "gene_reaction_rule": "CEPT1"}, {"subsystem": "Glycerophospholipid Metabolism", "name": "Ethanolamine phosphotransferase (C18:2,C16:0)", "upper_bound": 1000.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["CEPTE_18_2_16_0"]}, "metabolites": {"cdpea_c": -1.0, "dag_hs_18_2_16_0_c": -1.0, "h_c": 1.0, "pe_hs_18_2_16_0_c": 1.0, "cmp_c": 1.0}, "id": "CEPTE_18_2_16_0", "gene_reaction_rule": "CEPT1"}, {"subsystem": "Glycerophospholipid Metabolism", "name": "Ethanolamine phosphotransferase (C18:2,C18:1)", "upper_bound": 1000.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["CEPTE_18_2_18_1"]}, "metabolites": {"cdpea_c": -1.0, "pe_hs_18_2_18_1_c": 1.0, "dag_hs_18_2_18_1_c": -1.0, "h_c": 1.0, "cmp_c": 1.0}, "id": "CEPTE_18_2_18_1", "gene_reaction_rule": "CEPT1"}, {"subsystem": "Transport, Extracellular", "name": "CGMPt", "upper_bound": 1000.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["CGMPt"]}, "metabolites": {"h2o_c": -1.0, "atp_c": -1.0, "h_c": 1.0, "adp_c": 1.0, "35cgmp_e": 1.0, "pi_c": 1.0, "35cgmp_c": -1.0}, "id": "CGMPt", "gene_reaction_rule": "Abcc4_1_e"}, {"subsystem": "Glycerophospholipid Metabolism", "name": "CHLP", "upper_bound": 1000.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["CHLP"]}, "metabolites": {"chol_c": 1.0, "cholp_c": -1.0, "h2o_c": -1.0, "pi_c": 1.0}, "id": "CHLP", "gene_reaction_rule": "Phospho1_AT1"}, {"subsystem": "Glycerophospholipid Metabolism", "name": "Choline phosphate cytididyltransferase", "upper_bound": 1000.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["CHLPCTD"]}, "metabolites": {"ctp_c": -1.0, "cholp_c": -1.0, "ppi_c": 1.0, "cdpchol_c": 1.0, "h_c": -1.0}, "id": "CHLPCTD", "gene_reaction_rule": "Pcyt1a_AT1 or Pcyt1b_AT1"}, {"subsystem": "Glycerophospholipid Metabolism", "name": "Choline kinase", "upper_bound": 1000.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["CHOLK"]}, "metabolites": {"chol_c": -1.0, "cholp_c": 1.0, "h_c": 1.0, "atp_c": -1.0, "adp_c": 1.0}, "id": "CHOLK", "gene_reaction_rule": "Chkl_AT2 or Chkl_AT1 or Chk_AT2 or Chk_AT1"}, {"subsystem": "Transport, Extracellular", "name": "CHOLt4", "upper_bound": 1000.0, "lower_bound": -1000.0, "notes": {"original_bigg_ids": ["CHOLt4"]}, "metabolites": {"chol_c": 1.0, "na1_c": 1.0, "na1_e": -1.0, "chol_e": -1.0}, "id": "CHOLt4", "gene_reaction_rule": "Slc5a7_AT1"}, {"subsystem": "Transport, Extracellular", "name": "CO2 transporter via diffusion", "upper_bound": 1000.0, "lower_bound": -1000.0, "notes": {"original_bigg_ids": ["CO2t"]}, "metabolites": {"co2_c": 1.0, "co2_e": -1.0}, "id": "CO2t", "gene_reaction_rule": ""}, {"subsystem": "Transport, Extracellular", "name": "COt", "upper_bound": 1000.0, "lower_bound": -1000.0, "notes": {"original_bigg_ids": ["COt"]}, "metabolites": {"co_c": -1.0, "co_e": 1.0}, "id": "COt", "gene_reaction_rule": ""}, {"subsystem": "Heme Biosynthesis", "name": "Coproporphyrinogen oxidase (O2 required)", "upper_bound": 1000.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["CPPPGO"]}, "metabolites": {"o2_c": -1.0, "h2o_c": 2.0, "pppg9_c": 1.0, "cpppg3_c": -1.0, "h_c": -2.0, "co2_c": 2.0}, "id": "CPPPGO", "gene_reaction_rule": "Cpox_AT1"}, {"subsystem": "Transport, Extracellular", "name": "CYStec", "upper_bound": 1000.0, "lower_bound": -1000.0, "notes": {"original_bigg_ids": ["CYStec"]}, "metabolites": {"cys__L_c": 1.0, "cys__L_e": -1.0}, "id": "CYStec", "gene_reaction_rule": "Slc43a2_AT1"}, {"subsystem": "Nucleotides", "name": "Cytidylate kinase (CMP)", "upper_bound": 1000.0, "lower_bound": -1000.0, "notes": {"original_bigg_ids": ["CYTK1"]}, "metabolites": {"cdp_c": 1.0, "adp_c": 1.0, "atp_c": -1.0, "cmp_c": -1.0}, "id": "CYTK1", "gene_reaction_rule": "UmpK_AT1"}, {"subsystem": "Transport, Extracellular", "name": "D lactate transport via proton symport", "upper_bound": 1000.0, "lower_bound": -1000.0, "notes": {"original_bigg_ids": ["D_DASH_LACt2"]}, "metabolites": {"lac__D_e": -1.0, "h_e": -1.0, "lac__D_c": 1.0, "h_c": 1.0}, "id": "D_LACt2", "gene_reaction_rule": "Slc16a1_AT1"}, {"subsystem": "Glycerophospholipid Metabolism", "name": "Diacylglycerol phosphate kinase (homo sapiens, C16:0, C16:0)", "upper_bound": 1000.0, "lower_bound": -1000.0, "notes": {"original_bigg_ids": ["DAGK_hs_16_0_16_0"]}, "metabolites": {"pa_hs_16_0_16_0_c": 1.0, "dag_hs_16_0_16_0_c": -1.0, "h_c": 1.0, "adp_c": 1.0, "atp_c": -1.0}, "id": "DAGK_hs_16_0_16_1", "gene_reaction_rule": "Dgkb_AT2 or Dgkz_AT3 or Dgkz_AT1 or Dgkb_AT1 or Dgkb_AT1 or Dgkd_AT2 or Dgkz_AT2 or Dgkd_AT1 or Dgka_AT1 or Dgkq_AT1 or Dgkh_AT2 or Dgki_AT1 or Dgkh_AT1 or Dgkg_AT1 or Dgke_AT1"}, {"subsystem": "Glycerophospholipid Metabolism", "name": "Diacylglycerol phosphate kinase (homo sapiens, C16:0, C18:1)", "upper_bound": 1000.0, "lower_bound": -1000.0, "notes": {"original_bigg_ids": ["DAGK_hs_16_0_18_1"]}, "metabolites": {"dag_hs_16_0_18_1_c": -1.0, "atp_c": -1.0, "h_c": 1.0, "adp_c": 1.0, "pa_hs_16_0_18_1_c": 1.0}, "id": "DAGK_hs_16_0_18_3", "gene_reaction_rule": "Dgkb_AT2 or Dgkz_AT3 or Dgkz_AT1 or Dgkb_AT1 or Dgkb_AT1 or Dgkd_AT2 or Dgkz_AT2 or Dgkd_AT1 or Dgka_AT1 or Dgkq_AT1 or Dgkh_AT2 or Dgki_AT1 or Dgkh_AT1 or Dgkg_AT1 or Dgke_AT1"}, {"subsystem": "Glycerophospholipid Metabolism", "name": "Diacylglycerol phosphate kinase (homo sapiens, C16:0, C18:2)", "upper_bound": 1000.0, "lower_bound": -1000.0, "notes": {"original_bigg_ids": ["DAGK_hs_16_0_18_2"]}, "metabolites": {"pa_hs_16_0_18_2_c": 1.0, "dag_hs_16_0_18_2_c": -1.0, "atp_c": -1.0, "adp_c": 1.0, "h_c": 1.0}, "id": "DAGK_hs_16_0_18_4", "gene_reaction_rule": "Dgkb_AT2 or Dgkz_AT3 or Dgkz_AT1 or Dgkb_AT1 or Dgkb_AT1 or Dgkd_AT2 or Dgkz_AT2 or Dgkd_AT1 or Dgka_AT1 or Dgkq_AT1 or Dgkh_AT2 or Dgki_AT1 or Dgkh_AT1 or Dgkg_AT1 or Dgke_AT1"}, {"subsystem": "Glycerophospholipid Metabolism", "name": "Diacylglycerol phosphate kinase (homo sapiens, C18:1,C18:1)", "upper_bound": 1000.0, "lower_bound": -1000.0, "notes": {"original_bigg_ids": ["DAGK_hs_18_1_18_1"]}, "metabolites": {"dag_hs_18_1_18_1_c": -1.0, "pa_hs_18_1_18_1_c": 1.0, "h_c": 1.0, "atp_c": -1.0, "adp_c": 1.0}, "id": "DAGK_hs_18_1_18_3", "gene_reaction_rule": "Dgkb_AT2 or Dgkz_AT3 or Dgkz_AT1 or Dgkb_AT1 or Dgkb_AT1 or Dgkd_AT2 or Dgkz_AT2 or Dgkd_AT1 or Dgka_AT1 or Dgkq_AT1 or Dgkh_AT2 or Dgki_AT1 or Dgkh_AT1 or Dgkg_AT1 or Dgke_AT1"}, {"subsystem": "Glycerophospholipid Metabolism", "name": "Diacylglycerol phosphate kinase (homo sapiens, C18:1,C18:2)", "upper_bound": 1000.0, "lower_bound": -1000.0, "notes": {"original_bigg_ids": ["DAGK_hs_18_1_18_2"]}, "metabolites": {"dag_hs_18_1_18_2_c": -1.0, "pa_hs_18_1_18_2_c": 1.0, "h_c": 1.0, "atp_c": -1.0, "adp_c": 1.0}, "id": "DAGK_hs_18_1_18_4", "gene_reaction_rule": "Dgkb_AT2 or Dgkz_AT3 or Dgkz_AT1 or Dgkb_AT1 or Dgkb_AT1 or Dgkd_AT2 or Dgkz_AT2 or Dgkd_AT1 or Dgka_AT1 or Dgkq_AT1 or Dgkh_AT2 or Dgki_AT1 or Dgkh_AT1 or Dgkg_AT1 or Dgke_AT1"}, {"subsystem": "Glycerophospholipid Metabolism", "name": "Diacylglycerol phosphate kinase (homo sapiens, C18:2,C16:0)", "upper_bound": 1000.0, "lower_bound": -1000.0, "notes": {"original_bigg_ids": ["DAGK_hs_18_2_16_0"]}, "metabolites": {"pa_hs_18_2_16_0_c": 1.0, "dag_hs_18_2_16_0_c": -1.0, "h_c": 1.0, "adp_c": 1.0, "atp_c": -1.0}, "id": "DAGK_hs_18_2_16_0", "gene_reaction_rule": "Dgkb_AT2 or Dgkz_AT3 or Dgkz_AT1 or Dgkb_AT1 or Dgkb_AT1 or Dgkd_AT2 or Dgkz_AT2 or Dgkd_AT1 or Dgka_AT1 or Dgkq_AT1 or Dgkh_AT2 or Dgki_AT1 or Dgkh_AT1 or Dgkg_AT1 or Dgke_AT1"}, {"subsystem": "Glycerophospholipid Metabolism", "name": "Diacylglycerol phosphate kinase (homo sapiens, C18:2,C18:1)", "upper_bound": 1000.0, "lower_bound": -1000.0, "notes": {"original_bigg_ids": ["DAGK_hs_18_2_18_1"]}, "metabolites": {"dag_hs_18_2_18_1_c": -1.0, "atp_c": -1.0, "pa_hs_18_2_18_1_c": 1.0, "adp_c": 1.0, "h_c": 1.0}, "id": "DAGK_hs_18_2_18_1", "gene_reaction_rule": "Dgkb_AT2 or Dgkz_AT3 or Dgkz_AT1 or Dgkb_AT1 or Dgkb_AT1 or Dgkd_AT2 or Dgkz_AT2 or Dgkd_AT1 or Dgka_AT1 or Dgkq_AT1 or Dgkh_AT2 or Dgki_AT1 or Dgkh_AT1 or Dgkg_AT1 or Dgke_AT1"}, {"subsystem": "Pentose and Glucuronate Interconversions", "name": "DGULND", "upper_bound": 1000.0, "lower_bound": -1000.0, "notes": {"original_bigg_ids": ["DGULND"]}, "metabolites": {"xylu__L_c": 1.0, "co2_c": 1.0, "h_c": -1.0, "3dhguln_c": -1.0}, "id": "DGULND", "gene_reaction_rule": ""}, {"subsystem": "Transport, Extracellular", "name": "DHAAt1r", "upper_bound": 1000.0, "lower_bound": -1000.0, "notes": {"original_bigg_ids": ["DHAAt1r"]}, "metabolites": {"dhdascb_c": 1.0, "dhdascb_e": -1.0}, "id": "DHAAt1r", "gene_reaction_rule": "Slc2a1_1_e"}, {"subsystem": "'", "name": "Demand NADH", "upper_bound": 1000.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["DM_nadh"]}, "metabolites": {"nadh_c": -1.0, "h_c": 1.0, "nad_c": 1.0}, "id": "DM_nadh", "gene_reaction_rule": ""}, {"subsystem": "Tyrosine metabolism", "name": "DOPAMT", "upper_bound": 1000.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["DOPAMT"]}, "metabolites": {"amet_c": -1.0, "ahcys_c": 1.0, "h_c": 1.0, "dopa_c": -1.0, "3moxtyr_c": 1.0}, "id": "DOPAMT", "gene_reaction_rule": "Comt_AT1 or Comt_AT2"}, {"subsystem": "Transport, Extracellular", "name": "DOPAtu", "upper_bound": 1000.0, "lower_bound": -1000.0, "notes": {"original_bigg_ids": ["DOPAtu"]}, "metabolites": {"dopa_e": -1.0, "dopa_c": 1.0}, "id": "DOPAtu", "gene_reaction_rule": "Slc22a2_AT1 or Slc22a2_AT2 or Slc22a3_AT1"}, {"subsystem": "Glycolysis/Gluconeogenesis", "name": "Diphosphoglyceromutase", "upper_bound": 1000.0, "lower_bound": -1000.0, "notes": {"original_bigg_ids": ["DPGM"]}, "metabolites": {"23dpg_c": 1.0, "13dpg_c": -1.0, "h_c": 1.0}, "id": "DPGM", "gene_reaction_rule": "Bpgm_AT2 or Bpgm_AT1"}, {"subsystem": "Glycolysis/Gluconeogenesis", "name": "DPGase", "upper_bound": 1000.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["DPGase"]}, "metabolites": {"h2o_c": -1.0, "pi_c": 1.0, "23dpg_c": -1.0, "3pg_c": 1.0}, "id": "DPGase", "gene_reaction_rule": "Bpgm_AT2 or Bpgm_AT1"}, {"subsystem": "Glycolysis/Gluconeogenesis", "name": "Enolase", "upper_bound": 1000.0, "lower_bound": -1000.0, "notes": {"original_bigg_ids": ["ENO"]}, "metabolites": {"pep_c": 1.0, "h2o_c": 1.0, "2pg_c": -1.0}, "id": "ENO", "gene_reaction_rule": "Eno1_AT1"}, {"subsystem": "Glycerophospholipid Metabolism", "name": "Ethanolamine kinase", "upper_bound": 1000.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ETHAK"]}, "metabolites": {"adp_c": 1.0, "h_c": 1.0, "atp_c": -1.0, "etha_c": -1.0, "ethamp_c": 1.0}, "id": "ETHAK", "gene_reaction_rule": "ETNK2 or ETNK1 or Chk_AT1 or Chk_AT2"}, {"subsystem": "Transport, Extracellular", "name": "Ethanolamine transport via diffusion  extracellular ", "upper_bound": 1000.0, "lower_bound": -1000.0, "notes": {"original_bigg_ids": ["ETHAt"]}, "metabolites": {"etha_e": -1.0, "etha_c": 1.0}, "id": "ETHAt", "gene_reaction_rule": ""}, {"subsystem": "Glycerophospholipid Metabolism", "name": "ETHP", "upper_bound": 1000.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ETHP"]}, "metabolites": {"h2o_c": -1.0, "pi_c": 1.0, "etha_c": 1.0, "ethamp_c": -1.0}, "id": "ETHP", "gene_reaction_rule": "Phospho1_AT1"}, {"subsystem": "Fatty acid activation", "name": "Fatty acid  CoA ligase  hexadecanoate ", "upper_bound": 1000.0, "lower_bound": -1000.0, "notes": {"original_bigg_ids": ["FACOAL160"]}, "metabolites": {"atp_c": -1.0, "ppi_c": 1.0, "pmtcoa_c": 1.0, "coa_c": -1.0, "amp_c": 1.0, "hdca_c": -1.0}, "id": "FACOAL160", "gene_reaction_rule": "Acsl1_AT1"}, {"subsystem": "Fatty acid activation", "name": "Fatty acid  CoA ligase  octadecenoate ", "upper_bound": 1000.0, "lower_bound": -1000.0, "notes": {"original_bigg_ids": ["FACOAL181"]}, "metabolites": {"ocdcea_c": -1.0, "odecoa_c": 1.0, "atp_c": -1.0, "ppi_c": 1.0, "coa_c": -1.0, "amp_c": 1.0}, "id": "FACOAL181", "gene_reaction_rule": "Acsl1_AT1"}, {"subsystem": "Fatty acid activation", "name": "FACOAL1821", "upper_bound": 1000.0, "lower_bound": -1000.0, "notes": {"original_bigg_ids": ["FACOAL1821"]}, "metabolites": {"lnlc_c": -1.0, "atp_c": -1.0, "lnlccoa_c": 1.0, "ppi_c": 1.0, "coa_c": -1.0, "amp_c": 1.0}, "id": "FACOAL1821", "gene_reaction_rule": "Acsl1_AT1"}, {"subsystem": "Riboflavin Metabolism", "name": "FADDP", "upper_bound": 1000.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FADDP"]}, "metabolites": {"h2o_c": -1.0, "fmn_c": 1.0, "h_c": 2.0, "fad_c": -1.0, "amp_c": 1.0}, "id": "FADDP", "gene_reaction_rule": "EnpP1_AT1"}, {"subsystem": "Glycolysis/Gluconeogenesis", "name": "Fructose-bisphosphate aldolase", "upper_bound": 1000.0, "lower_bound": -1000.0, "notes": {"original_bigg_ids": ["FBA"]}, "metabolites": {"dhap_c": 1.0, "fdp_c": -1.0, "g3p_c": 1.0}, "id": "FBA", "gene_reaction_rule": "Aldoc_AT1 or Aldoa_AT2 or Aldoa_AT1 or Aldoa_AT3"}, {"subsystem": "Fructose and Mannose Metabolism", "name": "Fructose 2 6 bisphosphate 2 phosphatase", "upper_bound": 1000.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FBP26"]}, "metabolites": {"f26bp_c": -1.0, "h2o_c": -1.0, "pi_c": 1.0, "f6p_c": 1.0}, "id": "FBP26", "gene_reaction_rule": "Pfkfb4_AT1 or Pfkfb1_AT1 or Pfkfb3_AT1 or Pfkfb2_AT1 or Fbp2_AT1 or Fbp1_AT1"}, {"subsystem": "Heme Biosynthesis", "name": "Ferrochelatase", "upper_bound": 1000.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FCLT"]}, "metabolites": {"fe2_c": -1.0, "ppp9_c": -1.0, "h_c": 2.0, "pheme_c": 1.0}, "id": "FCLT", "gene_reaction_rule": "Fech_AT1 or Fech_AT2"}, {"subsystem": "Transport, Extracellular", "name": "Iron  II  transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "notes": {"original_bigg_ids": ["FE2t1"]}, "metabolites": {"fe2_c": 1.0, "fe2_e": -1.0}, "id": "FE2t", "gene_reaction_rule": ""}, {"subsystem": "Riboflavin Metabolism", "name": "FMN adenylyltransferase", "upper_bound": 1000.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["FMNAT"]}, "metabolites": {"fad_c": 1.0, "ppi_c": 1.0, "fmn_c": -1.0, "h_c": -1.0, "atp_c": -1.0}, "id": "FMNAT", "gene_reaction_rule": "FadS_AT1 or FadS_AT2"}, {"subsystem": "Transport, Extracellular", "name": "FRUt1r", "upper_bound": 1000.0, "lower_bound": -1000.0, "notes": {"original_bigg_ids": ["FRUt1r"]}, "metabolites": {"fru_e": -1.0, "fru_c": 1.0}, "id": "FRUt1r", "gene_reaction_rule": "Slc2a8_1_e or Slc2a7_1_e or Slc2a11_1_e or Slc2a2_1_e or Slc2a5_1_e"}, {"subsystem": "Citric Acid Cycle", "name": "Fumarase", "upper_bound": 1000.0, "lower_bound": -1000.0, "notes": {"original_bigg_ids": ["FUM"]}, "metabolites": {"mal__L_c": 1.0, "fum_c": -1.0, "h2o_c": -1.0}, "id": "FUM", "gene_reaction_rule": "Fh_AT1"}, {"subsystem": "Transport, Extracellular", "name": "Fumarate transport via diffusion (reversible)", "upper_bound": 1000.0, "lower_bound": -1000.0, "notes": {"original_bigg_ids": ["FUMtr"]}, "metabolites": {"fum_c": 1.0, "fum_e": -1.0}, "id": "FUMtr", "gene_reaction_rule": ""}, {"subsystem": "Aminosugar Metabolism", "name": "Glucosamine-6-phosphate deaminase", "upper_bound": 1000.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["G6PDA"]}, "metabolites": {"gam6p_c": -1.0, "nh4_c": 1.0, "h2o_c": -1.0, "f6p_c": 1.0}, "id": "G6PDA", "gene_reaction_rule": "Gnpda1_AT1"}, {"subsystem": "Pentose Phosphate Pathway", "name": "Glucose 6-phosphate dehydrogenase", "upper_bound": 1000.0, "lower_bound": -1000.0, "notes": {"original_bigg_ids": ["G6PDH2r"]}, "metabolites": {"6pgl_c": 1.0, "g6p_c": -1.0, "nadp_c": -1.0, "nadph_c": 1.0, "h_c": 1.0}, "id": "G6PDH2r", "gene_reaction_rule": "G6pd_AT1"}, {"subsystem": "Galactose metabolism", "name": "Galactokinase", "upper_bound": 1000.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["GALK"]}, "metabolites": {"adp_c": 1.0, "gal_c": -1.0, "atp_c": -1.0, "gal1p_c": 1.0, "h_c": 1.0}, "id": "GALKr", "gene_reaction_rule": "Galk1_AT1"}, {"subsystem": "Galactose metabolism", "name": "GALOR", "upper_bound": 1000.0, "lower_bound": -1000.0, "notes": {"original_bigg_ids": ["GALOR"]}, "metabolites": {"nadph_c": -1.0, "nadp_c": 1.0, "galt_c": 1.0, "gal_c": -1.0, "h_c": -1.0}, "id": "GALOR", "gene_reaction_rule": "Akr1a1_AT2 or Akr1a1_AT1 or Akr1b1_AT1"}, {"subsystem": "Galactose metabolism", "name": "Galactose 1 phosphate uridylyltransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "notes": {"original_bigg_ids": ["GALT"]}, "metabolites": {"udpgal_c": 1.0, "utp_c": -1.0, "ppi_c": 1.0, "h_c": -1.0, "gal1p_c": -1.0}, "id": "GALT", "gene_reaction_rule": "Galt_AT1 or Galt_AT3 or Galt_AT2"}, {"subsystem": "Galactose metabolism", "name": "UTP-glucose-1-phosphate uridylyltransferase (irreversible)", "upper_bound": 1000.0, "lower_bound": -1000.0, "notes": {"original_bigg_ids": ["GALU"]}, "metabolites": {"utp_c": -1.0, "ppi_c": 1.0, "udpg_c": 1.0, "h_c": -1.0, "g1p_c": -1.0}, "id": "GALUi", "gene_reaction_rule": "Ugp2_AT2 or Ugp2_AT1"}, {"subsystem": "Transport, Extracellular", "name": "GALt1r", "upper_bound": 1000.0, "lower_bound": -1000.0, "notes": {"original_bigg_ids": ["GALt1r"]}, "metabolites": {"gal_c": 1.0, "gal_e": -1.0}, "id": "GALt1r", "gene_reaction_rule": "Slc2a1_1_e or Slc2a3_1_e"}, {"subsystem": "Transport, Extracellular", "name": "GAMt1r", "upper_bound": 1000.0, "lower_bound": -1000.0, "notes": {"original_bigg_ids": ["GAMt1r"]}, "metabolites": {"gam_c": 1.0, "gam_e": -1.0}, "id": "GAMt1r", "gene_reaction_rule": "Slc2a4_1_e or Slc2a1_1_e"}, {"subsystem": "Glycolysis/Gluconeogenesis", "name": "Glyceraldehyde-3-phosphate dehydrogenase", "upper_bound": 1000.0, "lower_bound": -1000.0, "notes": {"original_bigg_ids": ["GAPD"]}, "metabolites": {"pi_c": -1.0, "13dpg_c": 1.0, "g3p_c": -1.0, "h_c": 1.0, "nad_c": -1.0, "nadh_c": 1.0}, "id": "GAPD", "gene_reaction_rule": "Gapdh_AT1"}, {"subsystem": "Glutathione Metabolism", "name": "GGLUCT", "upper_bound": 1000.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["GGLUCT"]}, "metabolites": {"gluala_e": -1.0, "ala__L_c": 1.0, "5oxpro_c": 1.0}, "id": "GGLUCT", "gene_reaction_rule": "Gctg_AT1"}, {"subsystem": "Nucleotides", "name": "Guanylate kinase (GMP:ATP)", "upper_bound": 1000.0, "lower_bound": -1000.0, "notes": {"original_bigg_ids": ["GK1"]}, "metabolites": {"gmp_c": -1.0, "gdp_c": 1.0, "atp_c": -1.0, "adp_c": 1.0}, "id": "GK1", "gene_reaction_rule": "Guk1_AT1"}, {"subsystem": "Transport, Extracellular", "name": "Glucose transport  uniport ", "upper_bound": 1000.0, "lower_bound": -1000.0, "notes": {"original_bigg_ids": ["GLCt1r"]}, "metabolites": {"glc__D_c": 1.0, "glc__D_e": -1.0}, "id": "GLCt1", "gene_reaction_rule": "Slc2a3_1_e or Slc2a1_1_e or Slc2a4_1_e"}, {"subsystem": "Glutamate metabolism", "name": "Glutamine synthetase", "upper_bound": 1000.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["GLNS"]}, "metabolites": {"atp_c": -1.0, "glu__L_c": -1.0, "h_c": 1.0, "adp_c": 1.0, "pi_c": 1.0, "nh4_c": -1.0, "gln__L_c": 1.0}, "id": "GLNS", "gene_reaction_rule": "Glul_AT1"}, {"subsystem": "Transport, Extracellular", "name": "GLNt4", "upper_bound": 1000.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["GLNt4"]}, "metabolites": {"gln__L_e": -1.0, "na1_c": 1.0, "na1_e": -1.0, "gln__L_c": 1.0}, "id": "GLNt4", "gene_reaction_rule": "Slc38a4_AT1 or Slc38a1_AT1 or Slc6a14_AT1 or Slc38a2_AT1"}, {"subsystem": "Glutathione Metabolism", "name": "Gamma-glutamylcysteine synthetase", "upper_bound": 1000.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["GLUCYS"]}, "metabolites": {"cys__L_c": -1.0, "glucys_c": 1.0, "atp_c": -1.0, "glu__L_c": -1.0, "h_c": 1.0, "adp_c": 1.0, "pi_c": 1.0}, "id": "GLUCYS", "gene_reaction_rule": "Gclm_AT1 and Gclc_AT1"}, {"subsystem": "Transport, Extracellular", "name": "Glycerol transport via channel", "upper_bound": 1000.0, "lower_bound": -1000.0, "notes": {"original_bigg_ids": ["GLYCt"]}, "metabolites": {"glyc_e": 1.0, "glyc_c": -1.0}, "id": "GLYCt", "gene_reaction_rule": ""}, {"subsystem": "Glycerophospholipid Metabolism", "name": "Glycerol kinase", "upper_bound": 1000.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["GLYK"]}, "metabolites": {"glyc3p_c": 1.0, "glyc_c": -1.0, "adp_c": 1.0, "atp_c": -1.0, "h_c": 1.0}, "id": "GLYK", "gene_reaction_rule": "Gkp3_AT1 or Gk_AT1 or Gk_AT2 or Gk2_AT1"}, {"subsystem": "Pyruvate Metabolism", "name": "Hydroxyacylglutathione hydrolase", "upper_bound": 1000.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["GLYOX"]}, "metabolites": {"lgt__S_c": -1.0, "h2o_c": -1.0, "gthrd_c": 1.0, "lac__D_c": 1.0, "h_c": 1.0}, "id": "GLYOX", "gene_reaction_rule": "Hagh_AT1"}, {"subsystem": "Transport, Extracellular", "name": "GLYt7 LPAREN 211 RPAREN r", "upper_bound": 1000.0, "lower_bound": -1000.0, "notes": {"original_bigg_ids": ["GLYt7_LPAREN_211_RPAREN_r"]}, "metabolites": {"na1_c": 2.0, "na1_e": -2.0, "cl_e": -1.0, "cl_c": 1.0, "gly_e": -1.0, "gly_c": 1.0}, "id": "GLYt7_211_r", "gene_reaction_rule": "Slc6a9_AT1 or Slc6a9_AT2"}, {"subsystem": "Nucleotides", "name": "GMP reductase", "upper_bound": 1000.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["GMPR"]}, "metabolites": {"nadp_c": 1.0, "nadph_c": -1.0, "nh4_c": 1.0, "gmp_c": -1.0, "h_c": -2.0, "imp_c": 1.0}, "id": "GMPR", "gene_reaction_rule": "GmpR_AT1"}, {"subsystem": "Nucleotides", "name": "GMP synthase", "upper_bound": 1000.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["GMPS2"]}, "metabolites": {"xmp_c": -1.0, "h2o_c": -1.0, "gmp_c": 1.0, "atp_c": -1.0, "ppi_c": 1.0, "amp_c": 1.0, "gln__L_c": -1.0, "glu__L_c": 1.0, "h_c": 2.0}, "id": "GMPS2", "gene_reaction_rule": "Gmps_AT1"}, {"subsystem": "Pentose Phosphate Pathway", "name": "Phosphogluconate dehydrogenase", "upper_bound": 1000.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["GND"]}, "metabolites": {"6pgc_c": -1.0, "co2_c": 1.0, "nadph_c": 1.0, "ru5p__D_c": 1.0, "nadp_c": -1.0}, "id": "GND", "gene_reaction_rule": "Pgd_AT1"}, {"subsystem": "Diacylglycerol Synthesis", "name": "Glycerol-3-phosphate acyltransferase (C16:0)", "upper_bound": 1000.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["GPAM_hs_16_0"]}, "metabolites": {"pmtcoa_c": -1.0, "alpa_hs_16_0_c": 1.0, "glyc3p_c": -1.0, "coa_c": 1.0}, "id": "GPAM_hs_16_1", "gene_reaction_rule": "Gpam_AT1"}, {"subsystem": "Diacylglycerol 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{"subsystem": "Ascorbate and Aldarate Metabolism", "name": "GTHDH", "upper_bound": 1000.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["GTHDH"]}, "metabolites": {"dhdascb_c": -1.0, "ascb__L_c": 1.0, "gthrd_c": -2.0, "gthox_c": 1.0}, "id": "GTHDH", "gene_reaction_rule": ""}, {"subsystem": "Glutamate metabolism", "name": "Glutathione oxidoreductase", "upper_bound": 1000.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["GTHO"]}, "metabolites": {"nadph_c": -1.0, "nadp_c": 1.0, "gthrd_c": 2.0, "h_c": -1.0, "gthox_c": -1.0}, "id": "GTHOr", "gene_reaction_rule": "Gsr_AT2"}, {"subsystem": "Transport, Extracellular", "name": "Oxidized glutathione irreversible active transport (rbc)", "upper_bound": 1000.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["GTHOXti2"]}, "metabolites": {"h2o_c": -1.0, "atp_c": -1.0, "h_c": 1.0, "adp_c": 1.0, "gthox_e": 1.0, "pi_c": 1.0, "gthox_c": -1.0}, "id": "GTHOXti2", "gene_reaction_rule": ""}, {"subsystem": "Glutathione Metabolism", "name": 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{"subsystem": "Pyruvate Metabolism", "name": "Lactoylglutathione lyase", "upper_bound": 1000.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["LGTHL"]}, "metabolites": {"gthrd_c": -1.0, "lgt__S_c": 1.0, "mthgxl_c": -1.0}, "id": "LGTHL", "gene_reaction_rule": "Glo1_AT1"}, {"subsystem": "Carnitine shuttle", "name": "LNLCCPT1", "upper_bound": 1000.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["LNLCCPT1"]}, "metabolites": {"crn_c": -1.0, "lnlccrn_c": 1.0, "coa_c": 1.0, "lnlccoa_c": -1.0}, "id": "LNLCCPT1", "gene_reaction_rule": "Cpt1a_AT1"}, {"subsystem": "Fatty acid activation", "name": "Carnitine transferase", "upper_bound": 1000.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["LNLCCPT2rbc"]}, "metabolites": {"crn_c": 1.0, "lnlccrn_c": -1.0, "coa_c": -1.0, "lnlccoa_c": 1.0}, "id": "LNLCCPT2rbc", "gene_reaction_rule": "Acsl1_AT1"}, {"subsystem": "Transport, Extracellular", "name": "LNLCt", "upper_bound": 1000.0, "lower_bound": -1000.0, "notes": {"original_bigg_ids": 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"r1p_c": -1.0, "h_c": -1.0}, "id": "NP1", "gene_reaction_rule": "Np_AT1"}, {"subsystem": "Transport, Extracellular", "name": "NRPPHRtu", "upper_bound": 1000.0, "lower_bound": -1000.0, "notes": {"original_bigg_ids": ["NRPPHRtu"]}, "metabolites": {"nrpphr_c": 1.0, "nrpphr_e": -1.0}, "id": "NRPPHRtu", "gene_reaction_rule": "Slc22a2_AT2 or Slc22a2_AT1 or Slc22a3_AT1"}, {"subsystem": "NAD Metabolism", "name": "NT5C", "upper_bound": 1000.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["NT5C"]}, "metabolites": {"nicrnt_c": -1.0, "h2o_c": -1.0, "pi_c": 1.0, "nicrns_c": 1.0}, "id": "NT5C", "gene_reaction_rule": "Nt5C2_AT1"}, {"subsystem": "Purine Catabolism", "name": "5'-nucleotidase (IMP)", "upper_bound": 1000.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["NTD11"]}, "metabolites": {"h2o_c": -1.0, "pi_c": 1.0, "imp_c": -1.0, "ins_c": 1.0}, "id": "NTD11", "gene_reaction_rule": "Nt5C2_AT1"}, {"subsystem": "Pyrimidine Catabolism", "name": "5'-nucleotidase (UMP)", "upper_bound": 1000.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["NTD2"]}, "metabolites": {"uri_c": 1.0, "h2o_c": -1.0, "pi_c": 1.0, "ump_c": -1.0}, "id": "NTD2", "gene_reaction_rule": "Nt5C3_AT1"}, {"subsystem": "NAD Metabolism", "name": "Nicotinamide ribonucleotide phosphohydrolase", "upper_bound": 1000.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["NTD5_a"]}, "metabolites": {"h2o_c": -1.0, "pi_c": 1.0, "nmn_c": -1.0, "rnam_c": 1.0}, "id": "NMNHYD", "gene_reaction_rule": "Nt5C_AT1"}, {"subsystem": "Nucleotides", "name": "5'-nucleotidase (AMP)", "upper_bound": 1000.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["NTD7"]}, "metabolites": {"h2o_c": -1.0, "pi_c": 1.0, "adn_c": 1.0, "amp_c": -1.0}, "id": "NTD7", "gene_reaction_rule": "Nt5C2_AT1"}, {"subsystem": "Nucleotides", "name": "5'-nucleotidase (GMP)", "upper_bound": 1000.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["NTD9"]}, "metabolites": {"h2o_c": -1.0, "gmp_c": -1.0, "pi_c": 1.0, "gsn_c": 1.0}, "id": "NTD9", "gene_reaction_rule": "Nt5C2_AT1"}, {"subsystem": "Transport, Extracellular", "name": "NaKt", "upper_bound": 1000.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["NaKt"]}, "metabolites": {"h2o_c": -1.0, "atp_c": -1.0, "na1_c": -3.0, "na1_e": 3.0, "h_c": 1.0, "adp_c": 1.0, "k_c": 2.0, "pi_c": 1.0, "k_e": -2.0}, "objective_coefficient": 1.0, "id": "NaKt", "gene_reaction_rule": "Atp1a1b1 or Atp1a1b2 or Atp1a1b3 or Atp1a1b4"}, {"subsystem": "Transport, Extracellular", "name": "O2 transport  diffusion ", "upper_bound": 1000.0, "lower_bound": -1000.0, "notes": {"original_bigg_ids": ["O2t"]}, "metabolites": {"o2_c": 1.0, "o2_e": -1.0}, "id": "O2t", "gene_reaction_rule": ""}, {"subsystem": "Transport, Extracellular", "name": "Octadecenoate  n C181  transport in via uniport", "upper_bound": 1000.0, "lower_bound": -1000.0, "notes": {"original_bigg_ids": ["OCDCEAtr"]}, "metabolites": {"ocdcea_c": 1.0, "ocdcea_e": -1.0}, "id": "OCDCEAt", "gene_reaction_rule": ""}, {"subsystem": "Pyrimidine Biosynthesis", "name": "Orotidine-5'-phosphate decarboxylase", "upper_bound": 1000.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["OMPDC"]}, "metabolites": {"ump_c": 1.0, "co2_c": 1.0, "h_c": -1.0, "orot5p_c": -1.0}, "id": "OMPDC", "gene_reaction_rule": "Umps_AT1"}, {"subsystem": "Glutathione Metabolism", "name": "OPAH", "upper_bound": 1000.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["OPAHir"]}, "metabolites": {"h2o_c": -2.0, "atp_c": -1.0, "glu__L_c": 1.0, "5oxpro_c": -1.0, "h_c": 1.0, "adp_c": 1.0, "pi_c": 1.0}, "id": "OPAH", "gene_reaction_rule": "Oplah_AT1"}, {"subsystem": "Urea cycle/amino group metabolism", "name": "Ornithine Decarboxylase", "upper_bound": 1000.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["ORNDC"]}, "metabolites": {"ptrc_c": 1.0, "co2_c": 1.0, "orn_c": -1.0, "h_c": -1.0}, "id": "ORNDC", "gene_reaction_rule": "Odc1_AT1"}, {"subsystem": "Transport, Extracellular", "name": "OROATP", "upper_bound": 1000.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["OROATP"]}, "metabolites": {"orot_e": -1.0, "h_e": -1.0, "h_c": 1.0, "orot_c": 1.0}, "id": "OROATP", "gene_reaction_rule": ""}, {"subsystem": "Pyrimidine Biosynthesis", "name": "Orotate phosphoribosyltransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "notes": {"original_bigg_ids": ["ORPT"]}, "metabolites": {"ppi_c": -1.0, "prpp_c": 1.0, "orot_c": 1.0, "orot5p_c": -1.0}, "id": "ORPT", "gene_reaction_rule": "Umps_AT1"}, {"subsystem": "Nucleotides", "name": "3',5'-cyclic-nucleotide phosphodiesterase", "upper_bound": 1000.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PDE1"]}, "metabolites": {"h2o_c": -1.0, "camp_c": -1.0, "amp_c": 1.0, "h_c": 1.0}, "id": "PDE1", "gene_reaction_rule": "Pde8a_AT5 or Pde8a_AT3 or Pde8a_AT2 or Pde7A_AT2 or Pde11A_AT1 or Pde8a_AT1 or Pde1C_AT1 or Pde4C_AT1 or Pde4B_AT1 or Pde2A_AT1 or Pde3A_AT1 or Pde3B_AT2 or Pde7A_AT1 or Pde8b_AT1 or Pde7B_AT1 or Pde4A_AT1 or Pde1A_AT2 or PDE10A or Pde1B_AT1 or Pde4D_AT1 or Pde1A_AT1 or Pde8a_AT4 or Pde3B_AT1"}, {"subsystem": "Vitamin B6 Metabolism", "name": "Pyridoxine 5'-phosphate oxidase", "upper_bound": 1000.0, "lower_bound": -1000.0, "notes": {"original_bigg_ids": ["PDX5PO"]}, "metabolites": {"h2o2_c": 1.0, "pydx5p_c": 1.0, "pdx5p_c": -1.0, "o2_c": -1.0}, "id": "PDX5POi", "gene_reaction_rule": "PnpO_AT1"}, {"subsystem": "Vitamin B6 Metabolism", "name": "Pyridoxine 5-phosphate phosphatase", "upper_bound": 1000.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PDXPP"]}, "metabolites": {"pydxn_c": 1.0, "h2o_c": -1.0, "pi_c": 1.0, "pdx5p_c": -1.0}, "id": "PDXPP", "gene_reaction_rule": "PdxP_AT1"}, {"subsystem": "Glycerophospholipid Metabolism", "name": "Phosphoethanolamine cytidyltransferase", "upper_bound": 1000.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PETHCT"]}, "metabolites": {"cdpea_c": 1.0, "ctp_c": -1.0, "ppi_c": 1.0, "h_c": -1.0, "ethamp_c": -1.0}, "id": "PETHCT", "gene_reaction_rule": "Pcyt2_AT1"}, {"subsystem": "Glycolysis/Gluconeogenesis", "name": "Phosphofructokinase", "upper_bound": 1000.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PFK"]}, "metabolites": {"fdp_c": 1.0, "atp_c": -1.0, "h_c": 1.0, "adp_c": 1.0, "f6p_c": -1.0}, "id": "PFK", "gene_reaction_rule": "Pfkl_AT2 or Pfkm_AT1 or Pfkl_AT1"}, {"subsystem": "Fructose and Mannose Metabolism", "name": "6 phosphofructo 2 kinase", "upper_bound": 1000.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PFK26"]}, "metabolites": {"f26bp_c": 1.0, "f6p_c": -1.0, "h_c": 1.0, "atp_c": -1.0, "adp_c": 1.0}, "id": "PFK26", "gene_reaction_rule": "Pfkfb1_AT1 or Pfkfb4_AT1 or Pfkfb3_AT1 or Pfkfb2_AT1"}, {"subsystem": "Glycolysis/Gluconeogenesis", "name": "Glucose-6-phosphate isomerase", "upper_bound": 1000.0, "lower_bound": -1000.0, "notes": {"original_bigg_ids": ["PGI"]}, "metabolites": {"g6p_c": -1.0, "f6p_c": 1.0}, "id": "PGI", "gene_reaction_rule": "Gpi_AT1"}, {"subsystem": "Glycolysis/Gluconeogenesis", "name": "Phosphoglycerate kinase", "upper_bound": 1000.0, "lower_bound": -1000.0, "notes": {"original_bigg_ids": ["PGK"]}, "metabolites": {"13dpg_c": 1.0, "adp_c": 1.0, "atp_c": -1.0, "3pg_c": -1.0}, "id": "PGK", "gene_reaction_rule": "Pgk1_AT1"}, {"subsystem": "Pentose Phosphate Pathway", "name": "6-phosphogluconolactonase", "upper_bound": 1000.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PGL"]}, "metabolites": {"6pgc_c": 1.0, "h2o_c": -1.0, "6pgl_c": -1.0, "h_c": 1.0}, "id": "PGL", "gene_reaction_rule": "Pgls_AT1"}, {"subsystem": "Glycolysis/Gluconeogenesis", "name": "Phosphoglycerate mutase", "upper_bound": 1000.0, "lower_bound": -1000.0, "notes": {"original_bigg_ids": ["PGM"]}, "metabolites": {"2pg_c": -1.0, "3pg_c": 1.0}, "id": "PGM", "gene_reaction_rule": "Bpgm_AT1 or Bpgm_AT2"}, {"subsystem": "Glycolysis/Gluconeogenesis", "name": "Phosphoglucomutase", "upper_bound": 1000.0, "lower_bound": -1000.0, "notes": {"original_bigg_ids": ["PGMT"]}, "metabolites": {"g6p_c": 1.0, "g1p_c": -1.0}, "id": "PGMT", "gene_reaction_rule": "PGM2"}, {"subsystem": "Phenylalanine metabolism", "name": "Phenylalanine transaminase", "upper_bound": 1000.0, "lower_bound": -1000.0, "notes": {"original_bigg_ids": ["PHETA1"]}, "metabolites": {"akg_c": -1.0, "phpyr_c": 1.0, "glu__L_c": 1.0, "phe__L_c": -1.0}, "id": "PHETA1", "gene_reaction_rule": "Got1_AT1"}, {"subsystem": "Transport, Extracellular", "name": "PHEtec", "upper_bound": 1000.0, "lower_bound": -1000.0, "notes": {"original_bigg_ids": ["PHEtec"]}, "metabolites": {"phe__L_e": -1.0, "phe__L_c": 1.0}, "id": "PHEtec", "gene_reaction_rule": "Slc43a2_AT1"}, {"subsystem": "Inositol Phosphate Metabolism", "name": "Phosphatidylinositol-4,5-bisphosphate 5-phosphatase (C16:0, C16:0)", "upper_bound": 1000.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PI45P5P_16_0_16_0"]}, "metabolites": {"h2o_c": -1.0, "pi_c": 1.0, "pail45p_hs_16_0_16_0_c": -1.0, "pail4p_hs_16_0_16_0_c": 1.0}, "id": "PI45P5P_16_0_16_0", "gene_reaction_rule": "Synj1_AT2 or 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"gene_reaction_rule": "Synj1_AT2 or Synj1_AT1"}, {"subsystem": "Inositol Phosphate Metabolism", "name": "Phosphatidylinositol-4,5-bisphosphate 5-phosphatase (C18:2, C18:1)", "upper_bound": 1000.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PI45P5P_18_2_18_1"]}, "metabolites": {"pail4p_hs_18_2_18_1_c": 1.0, "pail45p_hs_18_2_18_1_c": -1.0, "pi_c": 1.0, "h2o_c": -1.0}, "id": "PI45P5P_18_2_18_1", "gene_reaction_rule": "Synj1_AT2 or Synj1_AT1"}, {"subsystem": "Inositol Phosphate Metabolism", "name": "PI45PLC 16 0 16 0", "upper_bound": 1000.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PI45PLC_16_0_16_0"]}, "metabolites": {"dag_hs_16_0_16_0_c": 1.0, "mi145p_c": 1.0, "pail45p_hs_16_0_16_0_c": -1.0, "h2o_c": -1.0, "h_c": 1.0}, "id": "PI45PLC_16_0_16_0", "gene_reaction_rule": "Plcb3_AT1"}, {"subsystem": "Inositol Phosphate Metabolism", "name": "PI45PLC 16 0 18 1", "upper_bound": 1000.0, "lower_bound": 0.0, "notes": {"original_bigg_ids": ["PI45PLC_16_0_18_1"]}, "metabolites": 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["Pcyt1b.1"]}, "name": "PCYT1B", "id": "Pcyt1b_AT1"}, {"notes": {"original_bigg_ids": ["Pcyt1a.1"]}, "name": "PCYT1A", "id": "Pcyt1a_AT1"}, {"notes": {"original_bigg_ids": ["Chk.1"]}, "name": "None", "id": "Chk_AT1"}, {"notes": {"original_bigg_ids": ["Chkl.2"]}, "name": "None", "id": "Chkl_AT2"}, {"notes": {"original_bigg_ids": ["Chkl.1"]}, "name": "None", "id": "Chkl_AT1"}, {"notes": {"original_bigg_ids": ["Chk.2"]}, "name": "None", "id": "Chk_AT2"}, {"notes": {"original_bigg_ids": ["Slc5a7.1"]}, "name": "SLC5A7", "id": "Slc5a7_AT1"}, {"notes": {"original_bigg_ids": ["Cpox.1"]}, "name": "CPOX", "id": "Cpox_AT1"}, {"notes": {"original_bigg_ids": ["Slc43a2.1"]}, "name": "SLC43A2", "id": "Slc43a2_AT1"}, {"notes": {"original_bigg_ids": ["UmpK.1"]}, "name": "None", "id": "UmpK_AT1"}, {"notes": {"original_bigg_ids": ["Slc16a1.1"]}, "name": "SLC16A1", "id": "Slc16a1_AT1"}, {"notes": {"original_bigg_ids": ["Dgkd.1"]}, "name": "DGKD", "id": "Dgkd_AT1"}, {"notes": {"original_bigg_ids": ["Dgkz.3"]}, "name": "DGKZ", "id": "Dgkz_AT3"}, {"notes": {"original_bigg_ids": ["Dgkh.1"]}, "name": "DGKH", "id": "Dgkh_AT1"}, {"notes": {"original_bigg_ids": ["Dgkh.2"]}, "name": "DGKH", "id": "Dgkh_AT2"}, {"notes": {"original_bigg_ids": ["Dgkd.2"]}, "name": "DGKD", "id": "Dgkd_AT2"}, {"notes": {"original_bigg_ids": ["Dgkg.1"]}, "name": "DGKG", "id": "Dgkg_AT1"}, {"notes": {"original_bigg_ids": ["Dgkz.1"]}, "name": "DGKZ", "id": "Dgkz_AT1"}, {"notes": {"original_bigg_ids": ["Dgkb.2"]}, "name": "DGKB", "id": "Dgkb_AT2"}, {"notes": {"original_bigg_ids": ["Dgkq.1"]}, "name": "DGKQ", "id": "Dgkq_AT1"}, {"notes": {"original_bigg_ids": ["Dgkz.2"]}, "name": "DGKZ", "id": "Dgkz_AT2"}, {"notes": {"original_bigg_ids": ["Dgkb.1"]}, "name": "DGKB", "id": "Dgkb_AT1"}, {"notes": {"original_bigg_ids": ["Dgka.1"]}, "name": "DGKA", "id": "Dgka_AT1"}, {"notes": {"original_bigg_ids": ["Dgki.1"]}, "name": "DGKI", "id": "Dgki_AT1"}, {"notes": {"original_bigg_ids": ["Dgke.1"]}, "name": "DGKE", "id": "Dgke_AT1"}, {"notes": {"original_bigg_ids": ["Slc2a1.1-e"]}, "name": "None", "id": "Slc2a1_1_e"}, {"notes": {"original_bigg_ids": ["Comt.1"]}, "name": "COMT", "id": "Comt_AT1"}, {"notes": {"original_bigg_ids": ["Comt.2"]}, "name": "COMT", "id": "Comt_AT2"}, {"notes": {"original_bigg_ids": ["Slc22a3.1"]}, "name": "SLC22A3", "id": "Slc22a3_AT1"}, {"notes": {"original_bigg_ids": ["Slc22a2.1"]}, "name": "SLC22A2", "id": "Slc22a2_AT1"}, {"notes": {"original_bigg_ids": ["Slc22a2.2"]}, "name": "SLC22A2", "id": "Slc22a2_AT2"}, {"notes": {"original_bigg_ids": ["Bpgm.2"]}, "name": "BPGM", "id": "Bpgm_AT2"}, {"notes": {"original_bigg_ids": ["Bpgm.1"]}, "name": "BPGM", "id": "Bpgm_AT1"}, {"notes": {"original_bigg_ids": ["Eno1.1"]}, "name": "ENO1", "id": "Eno1_AT1"}, {"notes": {"original_bigg_ids": ["Acsl1.1"]}, "name": "ACSL1", "id": "Acsl1_AT1"}, {"notes": {"original_bigg_ids": ["EnpP1.1"]}, "name": "ENPP1", "id": "EnpP1_AT1"}, {"notes": {"original_bigg_ids": ["Aldoa.3"]}, "name": "ALDOA", "id": "Aldoa_AT3"}, {"notes": {"original_bigg_ids": ["Aldoa.1"]}, "name": "ALDOA", "id": "Aldoa_AT1"}, {"notes": {"original_bigg_ids": ["Aldoc.1"]}, "name": "ALDOC", "id": "Aldoc_AT1"}, {"notes": {"original_bigg_ids": ["Aldoa.2"]}, "name": "ALDOA", "id": "Aldoa_AT2"}, {"notes": {"original_bigg_ids": ["Fbp1.1"]}, "name": "FBP1", "id": "Fbp1_AT1"}, {"notes": {"original_bigg_ids": ["Fbp2.1"]}, "name": "FBP2", "id": "Fbp2_AT1"}, {"notes": {"original_bigg_ids": ["Pfkfb3.1"]}, "name": "PFKFB3", "id": "Pfkfb3_AT1"}, {"notes": {"original_bigg_ids": ["Pfkfb4.1"]}, "name": "PFKFB4", "id": "Pfkfb4_AT1"}, {"notes": {"original_bigg_ids": ["Pfkfb1.1"]}, "name": "PFKFB1", "id": "Pfkfb1_AT1"}, {"notes": {"original_bigg_ids": ["Pfkfb2.1"]}, "name": "PFKFB2", "id": "Pfkfb2_AT1"}, {"notes": {"original_bigg_ids": ["Fech.1"]}, "name": "FECH", "id": "Fech_AT1"}, {"notes": {"original_bigg_ids": ["Fech.2"]}, "name": "FECH", "id": "Fech_AT2"}, {"notes": {"original_bigg_ids": ["FadS.1"]}, "name": "None", "id": "FadS_AT1"}, {"notes": {"original_bigg_ids": ["FadS.2"]}, "name": "None", "id": "FadS_AT2"}, {"notes": {"original_bigg_ids": ["Slc2a5.1-e"]}, "name": "None", "id": "Slc2a5_1_e"}, {"notes": {"original_bigg_ids": ["Slc2a8.1-e"]}, "name": "None", "id": "Slc2a8_1_e"}, {"notes": {"original_bigg_ids": ["Slc2a7.1-e"]}, "name": "None", "id": "Slc2a7_1_e"}, {"notes": {"original_bigg_ids": ["Slc2a2.1-e"]}, "name": "None", "id": "Slc2a2_1_e"}, {"notes": {"original_bigg_ids": ["Slc2a11.1-e"]}, "name": "None", "id": "Slc2a11_1_e"}, {"notes": {"original_bigg_ids": ["Fh.1"]}, "name": "FH", "id": "Fh_AT1"}, {"notes": {"original_bigg_ids": ["Gnpda1.1"]}, "name": "GNPDA1", "id": "Gnpda1_AT1"}, {"notes": {"original_bigg_ids": ["G6pd.1"]}, "name": "G6PD", "id": "G6pd_AT1"}, {"notes": {"original_bigg_ids": ["Galk1.1"]}, "name": "GALK1", "id": "Galk1_AT1"}, {"notes": {"original_bigg_ids": ["Akr1a1.2"]}, "name": "AKR1A1", "id": "Akr1a1_AT2"}, {"notes": {"original_bigg_ids": ["Akr1b1.1"]}, "name": "AKR1B1", "id": "Akr1b1_AT1"}, {"notes": {"original_bigg_ids": ["Akr1a1.1"]}, "name": "AKR1A1", "id": "Akr1a1_AT1"}, {"notes": {"original_bigg_ids": ["Galt.3"]}, "name": "GALT", "id": "Galt_AT3"}, {"notes": {"original_bigg_ids": ["Galt.1"]}, "name": "GALT", "id": "Galt_AT1"}, {"notes": {"original_bigg_ids": ["Galt.2"]}, "name": "GALT", "id": "Galt_AT2"}, {"notes": {"original_bigg_ids": ["Ugp2.1"]}, "name": "UGP2", "id": "Ugp2_AT1"}, {"notes": {"original_bigg_ids": ["Ugp2.2"]}, "name": "UGP2", "id": "Ugp2_AT2"}, {"notes": {"original_bigg_ids": ["Slc2a3.1-e"]}, "name": "None", "id": "Slc2a3_1_e"}, {"notes": {"original_bigg_ids": ["Slc2a4.1-e"]}, "name": "None", "id": "Slc2a4_1_e"}, {"notes": {"original_bigg_ids": ["Gapdh.1"]}, "name": "GAPDH", "id": "Gapdh_AT1"}, {"notes": {"original_bigg_ids": ["Gctg.1"]}, "name": "None", "id": "Gctg_AT1"}, {"notes": {"original_bigg_ids": ["Guk1.1"]}, "name": "GUK1", "id": "Guk1_AT1"}, {"notes": {"original_bigg_ids": ["Glul.1"]}, "name": "GLUL", "id": "Glul_AT1"}, {"notes": {"original_bigg_ids": ["Gclc.1"]}, "name": "GCLC", "id": "Gclc_AT1"}, {"notes": {"original_bigg_ids": ["Gclm.1"]}, "name": "GCLM", "id": "Gclm_AT1"}, {"notes": {"original_bigg_ids": ["Gkp3.1"]}, "name": "None", "id": "Gkp3_AT1"}, {"notes": {"original_bigg_ids": ["Gk2.1"]}, "name": "GK2", "id": "Gk2_AT1"}, {"notes": {"original_bigg_ids": ["Gk.1"]}, "name": "GK", "id": "Gk_AT1"}, {"notes": {"original_bigg_ids": ["Gk.2"]}, "name": "GK", "id": "Gk_AT2"}, {"notes": {"original_bigg_ids": ["Hagh.1"]}, "name": "HAGH", "id": "Hagh_AT1"}, {"notes": {"original_bigg_ids": ["Slc6a9.2"]}, "name": "SLC6A9", "id": "Slc6a9_AT2"}, {"notes": {"original_bigg_ids": ["Slc6a9.1"]}, "name": "SLC6A9", "id": "Slc6a9_AT1"}, {"notes": {"original_bigg_ids": ["GmpR.1"]}, "name": "GMPR", "id": "GmpR_AT1"}, {"notes": {"original_bigg_ids": ["Gmps.1"]}, "name": "GMPS", "id": "Gmps_AT1"}, {"notes": {"original_bigg_ids": ["Pgd.1"]}, "name": "PGD", "id": "Pgd_AT1"}, {"notes": {"original_bigg_ids": ["Gpam.1"]}, "name": "GPAM", "id": "Gpam_AT1"}, {"notes": {"original_bigg_ids": ["Gsr.2"]}, "name": "GSR", "id": "Gsr_AT2"}, {"notes": {"original_bigg_ids": ["Prdx1.3"]}, "name": "PRDX1", "id": "Prdx1_AT3"}, {"notes": {"original_bigg_ids": ["Gpx1.2"]}, "name": "GPX1", "id": "Gpx1_AT2"}, {"notes": {"original_bigg_ids": ["Prdx2.1"]}, "name": "PRDX2", "id": "Prdx2_AT1"}, {"notes": {"original_bigg_ids": ["Prdx2.2"]}, "name": "PRDX2", "id": "Prdx2_AT2"}, {"notes": {"original_bigg_ids": ["Prdx1.2"]}, "name": "PRDX1", "id": "Prdx1_AT2"}, {"notes": {"original_bigg_ids": ["Prdx2.3"]}, "name": "PRDX2", "id": "Prdx2_AT3"}, {"notes": {"original_bigg_ids": ["Gpx1.1"]}, "name": "GPX1", "id": "Gpx1_AT1"}, {"notes": {"original_bigg_ids": ["Gpx4.1"]}, "name": "GPX4", "id": "Gpx4_AT1"}, {"notes": {"original_bigg_ids": ["Prdx1.1"]}, "name": "PRDX1", "id": "Prdx1_AT1"}, {"notes": {"original_bigg_ids": ["Gss.1"]}, "name": "GSS", "id": "Gss_AT1"}, {"notes": {"original_bigg_ids": ["Npr2.1"]}, "name": "NPR2", "id": "Npr2_AT1"}, {"notes": {"original_bigg_ids": ["Gucy2C.1"]}, "name": "GUCY2C", "id": "Gucy2C_AT1"}, {"notes": {"original_bigg_ids": ["Gucy1A3B2.1"]}, "name": "None", "id": "Gucy1A3B2_AT1"}, {"notes": {"original_bigg_ids": ["Npr2.2"]}, "name": "NPR2", "id": "Npr2_AT2"}, {"notes": {"original_bigg_ids": ["Npr1.1"]}, "name": "NPR1", "id": "Npr1_AT1"}, {"notes": {"original_bigg_ids": ["Gucy1A3B3.1"]}, "name": "None", "id": "Gucy1A3B3_AT1"}, {"notes": {"original_bigg_ids": ["Gucy1A2B2.1"]}, "name": "None", "id": "Gucy1A2B2_AT1"}, {"notes": {"original_bigg_ids": ["Gucy1A2B3.1"]}, "name": "None", "id": "Gucy1A2B3_AT1"}, {"notes": {"original_bigg_ids": ["Gucy2D.1"]}, "name": "GUCY2D", "id": "Gucy2D_AT1"}, {"notes": {"original_bigg_ids": ["Gucy2F.1"]}, "name": "GUCY2F", "id": "Gucy2F_AT1"}, {"notes": {"original_bigg_ids": ["HprT1.1"]}, "name": "HPRT1", "id": "HprT1_AT1"}, {"notes": {"original_bigg_ids": ["Slc5a1.1-e"]}, "name": "None", "id": "Slc5a1_1_e"}, {"notes": {"original_bigg_ids": ["Ca1.1"]}, "name": "CA1", "id": "Ca1_AT1"}, {"notes": {"original_bigg_ids": ["Ca3.1"]}, "name": "CA3", "id": "Ca3_AT1"}, {"notes": {"original_bigg_ids": ["Ca2.1"]}, "name": "CA2", "id": "Ca2_AT1"}, {"notes": {"original_bigg_ids": ["Slc4a1.1-e"]}, "name": "None", "id": "Slc4a1_1_e"}, {"notes": {"original_bigg_ids": ["Hk1.2"]}, "name": "HK1", "id": "Hk1_AT2"}, {"notes": {"original_bigg_ids": ["Hk1.5"]}, "name": "HK1", "id": "Hk1_AT5"}, {"notes": {"original_bigg_ids": ["Flj22761.1"]}, "name": "None", "id": "Flj22761_AT1"}, {"notes": {"original_bigg_ids": ["Hk2.1"]}, "name": "HK2", "id": "Hk2_AT1"}, {"notes": {"original_bigg_ids": ["Hk1.3"]}, "name": "HK1", "id": "Hk1_AT3"}, {"notes": {"original_bigg_ids": ["Hk3.1"]}, "name": "HK3", "id": "Hk3_AT1"}, {"notes": {"original_bigg_ids": ["Hk1.1"]}, "name": "HK1", "id": "Hk1_AT1"}, {"notes": {"original_bigg_ids": ["Hk1.4"]}, "name": "HK1", "id": "Hk1_AT4"}, {"notes": {"original_bigg_ids": ["Hmbs.1"]}, "name": "HMBS", "id": "Hmbs_AT1"}, {"notes": {"original_bigg_ids": ["Hmox1.1"]}, "name": "HMOX1", "id": "Hmox1_AT1"}, {"notes": {"original_bigg_ids": ["Hmox2.1"]}, "name": "HMOX2", "id": "Hmox2_AT1"}, {"notes": {"original_bigg_ids": ["Idh1.1"]}, "name": "IDH1", "id": "Idh1_AT1"}, {"notes": {"original_bigg_ids": ["ImpDH1.2"]}, "name": "IMPDH1", "id": "ImpDH1_AT2"}, {"notes": {"original_bigg_ids": ["ImpDH2.1"]}, "name": "IMPDH2", "id": "ImpDH2_AT1"}, {"notes": {"original_bigg_ids": ["ImpDH1.1"]}, "name": "IMPDH1", "id": "ImpDH1_AT1"}, {"notes": {"original_bigg_ids": ["Slc12a7.1-e"]}, "name": "None", "id": "Slc12a7_1_e"}, {"notes": {"original_bigg_ids": ["Ldha.1"]}, "name": "LDHA", "id": "Ldha_AT1"}, {"notes": {"original_bigg_ids": ["Ldhb.1"]}, "name": "LDHB", "id": "Ldhb_AT1"}, {"notes": {"original_bigg_ids": ["Glo1.1"]}, "name": "GLO1", "id": "Glo1_AT1"}, {"notes": {"original_bigg_ids": ["Pla2g4a.1"]}, "name": "PLA2G4A", "id": "Pla2g4a_AT1"}, {"notes": {"original_bigg_ids": ["Clc.1"]}, "name": "CLC", "id": "Clc_AT1"}, {"notes": {"original_bigg_ids": ["Lta4h.1"]}, "name": "LTA4H", "id": "Lta4h_AT1"}, {"notes": {"original_bigg_ids": ["Mpi.1"]}, "name": "MPI", "id": "Mpi_AT1"}, {"notes": {"original_bigg_ids": ["Mdh1.1"]}, "name": "MDH1", "id": "Mdh1_AT1"}, {"notes": {"original_bigg_ids": ["Me1.1"]}, "name": "ME1", "id": "Me1_AT1"}, {"notes": {"original_bigg_ids": ["Mat1a.1"]}, "name": "MAT1A", "id": "Mat1a_AT1"}, {"notes": {"original_bigg_ids": ["Slc43a1.1"]}, "name": "SLC43A1", "id": "Slc43a1_AT1"}, {"notes": {"original_bigg_ids": ["Synj1.2"]}, "name": "SYNJ1", "id": "Synj1_AT2"}, {"notes": {"original_bigg_ids": ["Inpp5d.1"]}, "name": "INPP5D", "id": "Inpp5d_AT1"}, {"notes": {"original_bigg_ids": ["Synj1.1"]}, "name": "SYNJ1", "id": "Synj1_AT1"}, {"notes": {"original_bigg_ids": ["Itpkb.1"]}, "name": "ITPKB", "id": "Itpkb_AT1"}, {"notes": {"original_bigg_ids": ["Itpka.1"]}, "name": "ITPKA", "id": "Itpka_AT1"}, {"notes": {"original_bigg_ids": ["Itpkc.1"]}, "name": "ITPKC", "id": "Itpkc_AT1"}, {"notes": {"original_bigg_ids": ["Impa1.1"]}, "name": "IMPA1", "id": "Impa1_AT1"}, {"notes": {"original_bigg_ids": ["Isyna1.1"]}, "name": "ISYNA1", "id": "Isyna1_AT1"}, {"notes": {"original_bigg_ids": ["Mtap.1"]}, "name": "MTAP", "id": "Mtap_AT1"}, {"notes": {"original_bigg_ids": ["Nadk.1"]}, "name": "NADK", "id": "Nadk_AT1"}, {"notes": {"original_bigg_ids": ["Nadsyn1.1"]}, "name": "NADSYN1", "id": "Nadsyn1_AT1"}, {"notes": {"original_bigg_ids": ["Slc5a5.1-e"]}, "name": "None", "id": "Slc5a5_1_e"}, {"notes": {"original_bigg_ids": ["Slc5a3.1-e"]}, "name": "None", "id": "Slc5a3_1_e"}, {"notes": {"original_bigg_ids": ["NME12.1"]}, "name": "None", "id": "NME12_AT1"}, {"notes": {"original_bigg_ids": ["NME6.1"]}, "name": "NME6", "id": "NME6_AT1"}, {"notes": {"original_bigg_ids": ["NME7.1"]}, "name": "NME7", "id": "NME7_AT1"}, {"notes": {"original_bigg_ids": ["NME3.1"]}, "name": "NME3", "id": "NME3_AT1"}, {"notes": {"original_bigg_ids": ["NME7.2"]}, "name": "NME7", "id": "NME7_AT2"}, {"notes": {"original_bigg_ids": ["NME12.2"]}, "name": "None", "id": "NME12_AT2"}, {"notes": {"original_bigg_ids": ["Rhbg.1-e"]}, "name": "None", "id": "Rhbg_1_e"}, {"notes": {"original_bigg_ids": ["Rhag.1-e"]}, "name": "None", "id": "Rhag_1_e"}, {"notes": {"original_bigg_ids": ["Nmnat3.1"]}, "name": "NMNAT3", "id": "Nmnat3_AT1"}, {"notes": {"original_bigg_ids": ["Np.1"]}, "name": "None", "id": "Np_AT1"}, {"notes": {"original_bigg_ids": ["Nt5C2.1"]}, "name": "NT5C2", "id": "Nt5C2_AT1"}, {"notes": {"original_bigg_ids": ["Nt5C3.1"]}, "name": "None", "id": "Nt5C3_AT1"}, {"notes": {"original_bigg_ids": ["Nt5C.1"]}, "name": "NT5C", "id": "Nt5C_AT1"}, {"notes": {"original_bigg_ids": ["Umps.1"]}, "name": "UMPS", "id": "Umps_AT1"}, {"notes": {"original_bigg_ids": ["Oplah.1"]}, "name": "OPLAH", "id": "Oplah_AT1"}, {"notes": {"original_bigg_ids": ["Odc1.1"]}, "name": "ODC1", "id": "Odc1_AT1"}, {"notes": {"original_bigg_ids": ["Pde3B.1"]}, "name": "PDE3B", "id": "Pde3B_AT1"}, {"notes": {"original_bigg_ids": ["Pde4D.1"]}, "name": "PDE4D", "id": "Pde4D_AT1"}, {"notes": {"original_bigg_ids": ["Pde1B.1"]}, "name": "PDE1B", "id": "Pde1B_AT1"}, {"notes": {"original_bigg_ids": ["Pde8a.1"]}, "name": "PDE8A", "id": "Pde8a_AT1"}, {"notes": {"original_bigg_ids": ["Pde11A.1"]}, "name": "PDE11A", "id": "Pde11A_AT1"}, {"notes": {"original_bigg_ids": ["Pde3A.1"]}, "name": "PDE3A", "id": "Pde3A_AT1"}, {"notes": {"original_bigg_ids": ["Pde2A.1"]}, "name": "PDE2A", "id": "Pde2A_AT1"}, {"notes": {"original_bigg_ids": ["Pde7B.1"]}, "name": "PDE7B", "id": "Pde7B_AT1"}, {"notes": {"original_bigg_ids": ["Pde7A.2"]}, "name": "PDE7A", "id": "Pde7A_AT2"}, {"notes": {"original_bigg_ids": ["Pde8a.2"]}, "name": "PDE8A", "id": "Pde8a_AT2"}, {"notes": {"original_bigg_ids": ["Pde1C.1"]}, "name": "PDE1C", "id": "Pde1C_AT1"}, {"notes": {"original_bigg_ids": ["Pde8a.4"]}, "name": "PDE8A", "id": "Pde8a_AT4"}, {"notes": {"original_bigg_ids": ["Pde3B.2"]}, "name": "PDE3B", "id": "Pde3B_AT2"}, {"notes": {"original_bigg_ids": ["Pde4C.1"]}, "name": "PDE4C", "id": "Pde4C_AT1"}, {"notes": {"original_bigg_ids": ["Pde1A.1"]}, "name": "PDE1A", "id": "Pde1A_AT1"}, {"notes": {"original_bigg_ids": ["Pde8a.3"]}, "name": "PDE8A", "id": "Pde8a_AT3"}, {"notes": {"original_bigg_ids": ["Pde4A.1"]}, "name": "PDE4A", "id": "Pde4A_AT1"}, {"notes": {"original_bigg_ids": ["Pde7A.1"]}, "name": "PDE7A", "id": "Pde7A_AT1"}, {"notes": {"original_bigg_ids": ["Pde4B.1"]}, "name": "PDE4B", "id": "Pde4B_AT1"}, {"notes": {"original_bigg_ids": ["Pde1A.2"]}, "name": "PDE1A", "id": "Pde1A_AT2"}, {"notes": {"original_bigg_ids": ["Pde8a.5"]}, "name": "PDE8A", "id": "Pde8a_AT5"}, {"notes": {"original_bigg_ids": ["Pde8b.1"]}, "name": "PDE8B", "id": "Pde8b_AT1"}, {"notes": {"original_bigg_ids": ["PnpO.1"]}, "name": "PNPO", "id": "PnpO_AT1"}, {"notes": {"original_bigg_ids": ["PdxP.1"]}, "name": "PDXP", "id": "PdxP_AT1"}, {"notes": {"original_bigg_ids": ["Pcyt2.1"]}, "name": "PCYT2", "id": "Pcyt2_AT1"}, {"notes": {"original_bigg_ids": ["Pfkm.1"]}, "name": "PFKM", "id": "Pfkm_AT1"}, {"notes": {"original_bigg_ids": ["Pfkl.2"]}, "name": "PFKL", "id": "Pfkl_AT2"}, {"notes": {"original_bigg_ids": ["Pfkl.1"]}, "name": "PFKL", "id": "Pfkl_AT1"}, {"notes": {"original_bigg_ids": ["Gpi.1"]}, "name": "GPI", "id": "Gpi_AT1"}, {"notes": {"original_bigg_ids": ["Pgk1.1"]}, "name": "PGK1", "id": "Pgk1_AT1"}, {"notes": {"original_bigg_ids": ["Pgls.1"]}, "name": "PGLS", "id": "Pgls_AT1"}, {"notes": {"original_bigg_ids": ["Got1.1"]}, "name": "GOT1", "id": "Got1_AT1"}, {"notes": {"original_bigg_ids": ["Plcb3.1"]}, "name": "PLCB3", "id": "Plcb3_AT1"}, {"notes": {"original_bigg_ids": ["Pip5k3.1"]}, "name": "None", "id": "Pip5k3_AT1"}, {"notes": {"original_bigg_ids": ["Pip5k2b.1"]}, "name": "None", "id": "Pip5k2b_AT1"}, {"notes": {"original_bigg_ids": ["Pip5k2a.1"]}, "name": "None", "id": "Pip5k2a_AT1"}, {"notes": {"original_bigg_ids": ["Pip5k1a.1"]}, "name": "PIP5K1A", "id": "Pip5k1a_AT1"}, {"notes": {"original_bigg_ids": ["Pip5k1b.1"]}, "name": "PIP5K1B", "id": "Pip5k1b_AT1"}, {"notes": {"original_bigg_ids": ["Pip5k3.3"]}, "name": "None", "id": "Pip5k3_AT3"}, {"notes": {"original_bigg_ids": ["Pip5k2c.1"]}, "name": "None", "id": "Pip5k2c_AT1"}, {"notes": {"original_bigg_ids": ["Pip5k3.2"]}, "name": "None", "id": "Pip5k3_AT2"}, {"notes": {"original_bigg_ids": ["Pip5k1c.1"]}, "name": "PIP5K1C", "id": "Pip5k1c_AT1"}, {"notes": {"original_bigg_ids": ["Pip5k2b.2"]}, "name": "None", "id": "Pip5k2b_AT2"}, {"notes": {"original_bigg_ids": ["Pi4kii.1"]}, "name": "None", "id": "Pi4kii_AT1"}, {"notes": {"original_bigg_ids": ["Pik4cb.1"]}, "name": "None", "id": "Pik4cb_AT1"}, {"notes": {"original_bigg_ids": ["Pik4ca.1"]}, "name": "None", "id": "Pik4ca_AT1"}, {"notes": {"original_bigg_ids": ["Pla2g2a.1"]}, "name": "PLA2G2A", "id": "Pla2g2a_AT1"}, {"notes": {"original_bigg_ids": ["Pla2g6.2"]}, "name": "PLA2G6", "id": "Pla2g6_AT2"}, {"notes": {"original_bigg_ids": ["Pla2g6.1"]}, "name": "PLA2G6", "id": "Pla2g6_AT1"}, {"notes": {"original_bigg_ids": ["Pmm2.1"]}, "name": "PMM2", "id": "Pmm2_AT1"}, {"notes": {"original_bigg_ids": ["Ppa2.4"]}, "name": "PPA2", "id": "Ppa2_AT4"}, {"notes": {"original_bigg_ids": ["Ppa2.1"]}, "name": "PPA2", "id": "Ppa2_AT1"}, {"notes": {"original_bigg_ids": ["Ppa2.2"]}, "name": "PPA2", "id": "Ppa2_AT2"}, {"notes": {"original_bigg_ids": ["Ppa2.3"]}, "name": "PPA2", "id": "Ppa2_AT3"}, {"notes": {"original_bigg_ids": ["Ppap2a.1"]}, "name": "PPAP2A", "id": "Ppap2a_AT1"}, {"notes": {"original_bigg_ids": ["Ppap2a.2"]}, "name": "PPAP2A", "id": "Ppap2a_AT2"}, {"notes": {"original_bigg_ids": ["Ppap2b.1"]}, "name": "PPAP2B", "id": "Ppap2b_AT1"}, {"notes": {"original_bigg_ids": ["Ppap2c.1"]}, "name": "PPAP2C", "id": "Ppap2c_AT1"}, {"notes": {"original_bigg_ids": ["Alad.1"]}, "name": "ALAD", "id": "Alad_AT1"}, {"notes": {"original_bigg_ids": ["Alad.2"]}, "name": "ALAD", "id": "Alad_AT2"}, {"notes": {"original_bigg_ids": ["Pgm1.1"]}, "name": "PGM1", "id": "Pgm1_AT1"}, {"notes": {"original_bigg_ids": ["Prps1l1.1"]}, "name": "PRPS1L1", "id": "Prps1l1_AT1"}, {"notes": {"original_bigg_ids": ["Prps1l1.2"]}, "name": "PRPS1L1", "id": "Prps1l1_AT2"}, {"notes": {"original_bigg_ids": ["Prps1.1"]}, "name": "PRPS1", "id": "Prps1_AT1"}, {"notes": {"original_bigg_ids": ["PdxK.1"]}, "name": "PDXK", "id": "PdxK_AT1"}, {"notes": {"original_bigg_ids": ["Aox1.1"]}, "name": "AOX1", "id": "Aox1_AT1"}, {"notes": {"original_bigg_ids": ["Pkm2.2"]}, "name": "None", "id": "Pkm2_AT2"}, {"notes": {"original_bigg_ids": ["Pkm2.1"]}, "name": "None", "id": "Pkm2_AT1"}, {"notes": {"original_bigg_ids": ["Pklr.2"]}, "name": "PKLR", "id": "Pklr_AT2"}, {"notes": {"original_bigg_ids": ["Pklr.1"]}, "name": "PKLR", "id": "Pklr_AT1"}, {"notes": {"original_bigg_ids": ["Pkm2.3"]}, "name": "None", "id": "Pkm2_AT3"}, {"notes": {"original_bigg_ids": ["Rfk.1"]}, "name": "RFK", "id": "Rfk_AT1"}, {"notes": {"original_bigg_ids": ["Nrk1.1"]}, "name": "None", "id": "Nrk1_AT1"}, {"notes": {"original_bigg_ids": ["Rpe.1"]}, "name": "RPE", "id": "Rpe_AT1"}, {"notes": {"original_bigg_ids": ["Rpe.2"]}, "name": "RPE", "id": "Rpe_AT2"}, {"notes": {"original_bigg_ids": ["Rpia.1"]}, "name": "RPIA", "id": "Rpia_AT1"}, {"notes": {"original_bigg_ids": ["Comtd1.1"]}, "name": "COMTD1", "id": "Comtd1_AT1"}, {"notes": {"original_bigg_ids": ["Sord.1"]}, "name": "SORD", "id": "Sord_AT1"}, {"notes": {"original_bigg_ids": ["Akr7a2.1"]}, "name": "AKR7A2", "id": "Akr7a2_AT1"}, {"notes": {"original_bigg_ids": ["Srm.1"]}, "name": "SRM", "id": "Srm_AT1"}, {"notes": {"original_bigg_ids": ["Sms.1"]}, "name": "SMS", "id": "Sms_AT1"}, {"notes": {"original_bigg_ids": ["Taldo1.1"]}, "name": "TALDO1", "id": "Taldo1_AT1"}, {"notes": {"original_bigg_ids": ["ThmtP.1"]}, "name": "None", "id": "ThmtP_AT1"}, {"notes": {"original_bigg_ids": ["Tkt.1"]}, "name": "TKT", "id": "Tkt_AT1"}, {"notes": {"original_bigg_ids": ["Tpk1.1"]}, "name": "TPK1", "id": "Tpk1_AT1"}, {"notes": {"original_bigg_ids": ["Tpi1.1"]}, "name": "TPI1", "id": "Tpi1_AT1"}, {"notes": {"original_bigg_ids": ["Gale.1"]}, "name": "GALE", "id": "Gale_AT1"}, {"notes": {"original_bigg_ids": ["Gale.2"]}, "name": "GALE", "id": "Gale_AT2"}, {"notes": {"original_bigg_ids": ["Ugdh.1"]}, "name": "UGDH", "id": "Ugdh_AT1"}, {"notes": {"original_bigg_ids": ["Uros.1"]}, "name": "UROS", "id": "Uros_AT1"}, {"notes": {"original_bigg_ids": ["Urod.1"]}, "name": "UROD", "id": "Urod_AT1"}, {"notes": {"original_bigg_ids": ["Slc14a1.1-e"]}, "name": "None", "id": "Slc14a1_1_e"}, {"notes": {"original_bigg_ids": ["Xylb.1"]}, "name": "XYLB", "id": "Xylb_AT1"}, {"notes": {"original_bigg_ids": ["Dcxr.1"]}, "name": "DCXR", "id": "Dcxr_AT1"}], "compartments": {"c": "cytosol", "e": "extracellular space"}, "metabolites": [{"notes": {"original_bigg_ids": ["13dpg_c"]}, "compartment": "c", "name": "3-Phospho-D-glyceroyl phosphate", "charge": 0, "id": "13dpg_c"}, {"notes": {"original_bigg_ids": ["23dpg_c"]}, "compartment": "c", "name": "2 3 Disphospho D glycerate C3H3O10P2", "charge": 0, "id": "23dpg_c"}, {"notes": {"original_bigg_ids": ["2kmb_c"]}, "compartment": "c", "name": "2-keto-4-methylthiobutyrate", "charge": 0, "id": "2kmb_c"}, {"notes": {"original_bigg_ids": ["2pg_c"]}, "compartment": "c", "name": "D-Glycerate 2-phosphate", "charge": 0, "id": "2pg_c"}, {"notes": {"original_bigg_ids": ["35cgmp_c"]}, "compartment": "c", "name": "3',5'-Cyclic GMP", "charge": 0, "id": "35cgmp_c"}, {"notes": {"original_bigg_ids": ["3dhguln_c"]}, "compartment": "c", "name": "3-Dehydro-L-gulonate", "charge": 0, "id": "3dhguln_c"}, {"notes": {"original_bigg_ids": ["3moxtyr_c"]}, "compartment": "c", "name": "3moxtyr c", "charge": 0, "id": "3moxtyr_c"}, {"notes": {"original_bigg_ids": ["3pg_c"]}, "compartment": "c", "name": "3-Phospho-D-glycerate", "charge": 0, "id": "3pg_c"}, {"notes": {"original_bigg_ids": ["4pyrdx_c"]}, "compartment": "c", "name": "4pyrdx c", "charge": 0, "id": "4pyrdx_c"}, {"notes": {"original_bigg_ids": ["5aop_c"]}, "compartment": "c", "name": "5-Amino-4-oxopentanoate", "charge": 0, "id": "5aop_c"}, {"notes": {"original_bigg_ids": ["5mdr1p_c"]}, "compartment": "c", "name": "5-Methylthio-5-deoxy-D-ribose 1-phosphate", "charge": 0, "id": "5mdr1p_c"}, {"notes": {"original_bigg_ids": ["5mdru1p_c"]}, "compartment": "c", "name": "5-Methylthio-5-deoxy-D-ribulose 1-phosphate", "charge": 0, "id": "5mdru1p_c"}, {"notes": {"original_bigg_ids": ["5mta_c"]}, "compartment": "c", "name": "5-Methylthioadenosine", "charge": 0, "id": "5mta_c"}, {"notes": {"original_bigg_ids": ["5oxpro_c"]}, "compartment": "c", "name": "5-Oxoproline", "charge": 0, "id": "5oxpro_c"}, {"notes": {"original_bigg_ids": ["6pgc_c"]}, "compartment": "c", "name": "6-Phospho-D-gluconate", "charge": 0, "id": "6pgc_c"}, {"notes": {"original_bigg_ids": ["6pgl_c"]}, "compartment": "c", "name": "6-phospho-D-glucono-1,5-lactone", "charge": 0, "id": "6pgl_c"}, {"notes": {"original_bigg_ids": ["ac_c"]}, "compartment": "c", "name": "Acetate", "charge": 0, "id": "ac_c"}, {"notes": {"original_bigg_ids": ["acald_c"]}, "compartment": "c", "name": "Acetaldehyde", "charge": 0, "id": "acald_c"}, {"notes": {"original_bigg_ids": ["acgam_c"]}, "compartment": "c", "name": "N-Acetyl-D-glucosamine", "charge": 0, "id": "acgam_c"}, {"notes": {"original_bigg_ids": ["acgam6p_c"]}, "compartment": "c", "name": "N-Acetyl-D-glucosamine 6-phosphate", "charge": 0, "id": "acgam6p_c"}, {"notes": {"original_bigg_ids": ["acmana_c"]}, "compartment": "c", "name": "N-Acetyl-D-mannosamine", "charge": 0, "id": "acmana_c"}, {"notes": {"original_bigg_ids": ["acmanap_c"]}, "compartment": "c", "name": "N-Acetyl-D-mannosamine 6-phosphate", "charge": 0, "id": "acmanap_c"}, {"notes": {"original_bigg_ids": ["acnam_c"]}, "compartment": "c", "name": "N-Acetylneuraminate", "charge": 0, "id": "acnam_c"}, {"notes": {"original_bigg_ids": ["acnamp_c"]}, "compartment": "c", "name": "Acnamp c", "charge": 0, "id": "acnamp_c"}, {"notes": {"original_bigg_ids": ["ade_c"]}, "compartment": "c", "name": "Adenine", "charge": 0, "id": "ade_c"}, {"notes": {"original_bigg_ids": ["adn_c"]}, "compartment": "c", "name": "Adenosine", "charge": 0, "id": "adn_c"}, {"notes": {"original_bigg_ids": ["adp_c"]}, "compartment": "c", "name": "ADP", "charge": 0, "id": "adp_c"}, {"notes": {"original_bigg_ids": ["adprbp_c"]}, "compartment": "c", "name": "Adprbp c", "charge": 0, "id": "adprbp_c"}, {"notes": {"original_bigg_ids": ["adrnl_c"]}, "compartment": "c", "name": "Adrnl c", "charge": 0, "id": "adrnl_c"}, {"notes": {"original_bigg_ids": ["ahcys_c"]}, "compartment": "c", "name": "S-Adenosyl-L-homocysteine", "charge": 0, "id": "ahcys_c"}, {"notes": {"original_bigg_ids": ["akg_c"]}, "compartment": "c", "name": "2-Oxoglutarate", "charge": 0, "id": "akg_c"}, {"notes": {"original_bigg_ids": ["ala_DASH_L_c"]}, "compartment": "c", "name": "L-Alanine", "charge": 0, "id": "ala__L_c"}, {"notes": {"original_bigg_ids": ["alpa_hs_16_0_c"]}, "compartment": "c", "name": "Lysophosphatidic acid (homo sapiens, C16:0)", "charge": 0, "id": "alpa_hs_16_0_c"}, {"notes": {"original_bigg_ids": ["alpa_hs_18_1_c"]}, "compartment": "c", "name": "Lysophosphatidic acid (homo sapiens, C18:1)", "charge": 0, "id": "alpa_hs_18_1_c"}, {"notes": {"original_bigg_ids": ["alpa_hs_18_2_c"]}, "compartment": "c", "name": "Lysophosphatidic acid (homo sapiens, C18:2)", "charge": 0, "id": "alpa_hs_18_2_c"}, {"notes": {"original_bigg_ids": ["amet_c"]}, "compartment": "c", "name": "S-Adenosyl-L-methionine", "charge": 0, "id": "amet_c"}, {"notes": {"original_bigg_ids": ["ametam_c"]}, "compartment": "c", "name": "S-Adenosylmethioninamine", "charge": 0, "id": "ametam_c"}, {"notes": {"original_bigg_ids": ["amp_c"]}, "compartment": "c", "name": "AMP", "charge": 0, "id": "amp_c"}, {"notes": {"original_bigg_ids": ["ap4a_c"]}, "compartment": "c", "name": "P1,P4-Bis(5'-adenosyl) tetraphosphate", "charge": 0, "id": "ap4a_c"}, {"notes": {"original_bigg_ids": ["arg_DASH_L_c"]}, "compartment": "c", "name": "L-Arginine", "charge": 0, "id": "arg__L_c"}, {"notes": {"original_bigg_ids": ["ascb_DASH_L_c"]}, "compartment": "c", "name": "L-Ascorbate", "charge": 0, "id": "ascb__L_c"}, {"notes": {"original_bigg_ids": ["atp_c"]}, "compartment": "c", "name": "ATP", "charge": 0, "id": "atp_c"}, {"notes": {"original_bigg_ids": ["band_c"]}, "compartment": "c", "name": "Band membrane protein (universal, erythrocyte -> 2.1,3,4.1)", "charge": 0, "id": "band_c"}, {"notes": {"original_bigg_ids": ["bandmt_c"]}, "compartment": "c", "name": "Band membrane protein (methylated, universal, erythrocyte -> 2.1,3,4.1)", "charge": 0, "id": "bandmt_c"}, {"notes": {"original_bigg_ids": ["bilglcur_c"]}, "compartment": "c", "name": "Bilglcur c", "charge": 0, "id": "bilglcur_c"}, {"notes": {"original_bigg_ids": ["bilirub_c"]}, "compartment": "c", "name": "Bilirubin", "charge": 0, "id": "bilirub_c"}, {"notes": {"original_bigg_ids": ["biliverd_c"]}, "compartment": "c", "name": "Biliverdin", "charge": 0, "id": "biliverd_c"}, {"notes": {"original_bigg_ids": ["ca2_c"]}, "compartment": "c", "name": "Calcium", "charge": 0, "id": "ca2_c"}, {"notes": {"original_bigg_ids": ["camp_c"]}, "compartment": "c", "name": "CAMP", "charge": 0, "id": "camp_c"}, {"notes": {"original_bigg_ids": ["cdp_c"]}, "compartment": "c", "name": "CDP", "charge": 0, "id": "cdp_c"}, {"notes": {"original_bigg_ids": ["cdpchol_c"]}, "compartment": "c", "name": "CDPcholine C14H25N4O11P2", "charge": 0, "id": "cdpchol_c"}, {"notes": {"original_bigg_ids": ["cdpdag_hs_16_0_16_0_c"]}, "compartment": "c", "name": "Cdpdag hs 16 0 16 0[c]", "charge": 0, "id": "cdpdag_hs_16_0_16_0_c"}, {"notes": {"original_bigg_ids": ["cdpdag_hs_16_0_18_1_c"]}, "compartment": "c", "name": "Cdpdag hs 16 0 18 1[c]", "charge": 0, "id": "cdpdag_hs_16_0_18_1_c"}, {"notes": {"original_bigg_ids": ["cdpdag_hs_16_0_18_2_c"]}, "compartment": "c", "name": "Cdpdag hs 16 0 18 2[c]", "charge": 0, "id": "cdpdag_hs_16_0_18_2_c"}, {"notes": {"original_bigg_ids": ["cdpdag_hs_18_1_18_1_c"]}, "compartment": "c", "name": "Cdpdag hs 18 1 18 1[c]", "charge": 0, "id": "cdpdag_hs_18_1_18_1_c"}, {"notes": {"original_bigg_ids": ["cdpdag_hs_18_1_18_2_c"]}, "compartment": "c", "name": "Cdpdag hs 18 1 18 2[c]", "charge": 0, "id": "cdpdag_hs_18_1_18_2_c"}, {"notes": {"original_bigg_ids": ["cdpdag_hs_18_2_16_0_c"]}, "compartment": "c", "name": "CDP diacylglycerol (homo sapiens, C18:2, C16:0)", "charge": 0, "id": "cdpdag_hs_18_2_16_0_c"}, {"notes": {"original_bigg_ids": ["cdpdag_hs_18_2_18_1_c"]}, "compartment": "c", "name": "CDP diacylglycerol (homo sapiens, C18:2, C18:1)", "charge": 0, "id": "cdpdag_hs_18_2_18_1_c"}, {"notes": {"original_bigg_ids": ["cdpea_c"]}, "compartment": "c", "name": "CDPethanolamine C11H19N4O11P2", "charge": 0, "id": "cdpea_c"}, {"notes": {"original_bigg_ids": ["chol_c"]}, "compartment": "c", "name": "Choline", "charge": 0, "id": "chol_c"}, {"notes": {"original_bigg_ids": ["cholp_c"]}, "compartment": "c", "name": "Choline phosphate C5H13NO4P", "charge": 0, "id": "cholp_c"}, {"notes": {"original_bigg_ids": ["cl_c"]}, "compartment": "c", "name": "Chloride", "charge": 0, "id": "cl_c"}, {"notes": {"original_bigg_ids": ["cmp_c"]}, "compartment": "c", "name": "CMP", "charge": 0, "id": "cmp_c"}, {"notes": {"original_bigg_ids": ["co_c"]}, "compartment": "c", "name": "Carbon monoxide", "charge": 0, "id": "co_c"}, {"notes": {"original_bigg_ids": ["co2_c"]}, "compartment": "c", "name": "CO2", "charge": 0, "id": "co2_c"}, {"notes": {"original_bigg_ids": ["coa_c"]}, "compartment": "c", "name": "Coenzyme A", "charge": 0, "id": "coa_c"}, {"notes": {"original_bigg_ids": ["cpppg3_c"]}, "compartment": "c", "name": "Coproporphyrinogen III", "charge": 0, "id": "cpppg3_c"}, {"notes": {"original_bigg_ids": ["crn_c"]}, "compartment": "c", "name": "L-Carnitine", "charge": 0, "id": "crn_c"}, {"notes": {"original_bigg_ids": ["ctp_c"]}, "compartment": "c", "name": "CTP", "charge": 0, "id": "ctp_c"}, {"notes": {"original_bigg_ids": ["cys_DASH_L_c"]}, "compartment": "c", "name": "L-Cysteine", "charge": 0, "id": "cys__L_c"}, {"notes": {"original_bigg_ids": ["dag_hs_16_0_16_0_c"]}, "compartment": "c", "name": "Dag hs 16 0 16 0[c]", "charge": 0, "id": "dag_hs_16_0_16_0_c"}, {"notes": {"original_bigg_ids": ["dag_hs_16_0_18_1_c"]}, "compartment": "c", "name": "Diacylglycerol (homo sapiens, C16:0, C18:1) cytosol", "charge": 0, "id": "dag_hs_16_0_18_1_c"}, {"notes": {"original_bigg_ids": ["dag_hs_16_0_18_2_c"]}, "compartment": "c", "name": "Dag hs 16 0 18 2[c]", "charge": 0, "id": "dag_hs_16_0_18_2_c"}, {"notes": {"original_bigg_ids": ["dag_hs_18_1_18_1_c"]}, "compartment": "c", "name": "Dag hs 18 1 18 1[c]", "charge": 0, "id": "dag_hs_18_1_18_1_c"}, {"notes": {"original_bigg_ids": ["dag_hs_18_1_18_2_c"]}, "compartment": "c", "name": "Dag hs 18 1 18 2[c]", "charge": 0, "id": "dag_hs_18_1_18_2_c"}, {"notes": {"original_bigg_ids": ["dag_hs_18_2_16_0_c"]}, "compartment": "c", "name": "Diacylglycerol (homo sapiens, C18:2, C16:0)", "charge": 0, "id": "dag_hs_18_2_16_0_c"}, {"notes": {"original_bigg_ids": ["dag_hs_18_2_18_1_c"]}, "compartment": "c", "name": "Diacylglycerol (homo sapiens, C18:2, C18:1)", "charge": 0, "id": "dag_hs_18_2_18_1_c"}, {"notes": {"original_bigg_ids": ["dhap_c"]}, "compartment": "c", "name": "Dihydroxyacetone phosphate", "charge": 0, "id": "dhap_c"}, {"notes": {"original_bigg_ids": ["dhdascb_c"]}, "compartment": "c", "name": "Dhdascb c", "charge": 0, "id": "dhdascb_c"}, {"notes": {"original_bigg_ids": ["dhmtp_c"]}, "compartment": "c", "name": "1,2-Dihydroxy-5-(methylthio)pent-1-en-3-one", "charge": 0, "id": "dhmtp_c"}, {"notes": {"original_bigg_ids": ["dkmpp_c"]}, "compartment": "c", "name": "2,3-diketo-5-methylthio-1-phosphopentane", "charge": 0, "id": "dkmpp_c"}, {"notes": {"original_bigg_ids": ["dnad_c"]}, "compartment": "c", "name": "Deamino-NAD+", "charge": 0, "id": "dnad_c"}, {"notes": {"original_bigg_ids": ["dopa_c"]}, "compartment": "c", "name": "Dopamine", "charge": 0, "id": "dopa_c"}, {"notes": {"original_bigg_ids": ["e4p_c"]}, "compartment": "c", "name": "D-Erythrose 4-phosphate", "charge": 0, "id": "e4p_c"}, {"notes": {"original_bigg_ids": ["etha_c"]}, "compartment": "c", "name": "Ethanolamine", "charge": 0, "id": "etha_c"}, {"notes": {"original_bigg_ids": ["ethamp_c"]}, "compartment": "c", "name": "Ethanolamine phosphate C2H7NO4P", "charge": 0, "id": "ethamp_c"}, {"notes": {"original_bigg_ids": ["f26bp_c"]}, "compartment": "c", "name": "D Fructose 2 6 bisphosphate C6H10O12P2", "charge": 0, "id": "f26bp_c"}, {"notes": {"original_bigg_ids": ["f6p_c"]}, "compartment": "c", "name": "D-Fructose 6-phosphate", "charge": 0, "id": "f6p_c"}, {"notes": {"original_bigg_ids": ["fad_c"]}, "compartment": "c", "name": "Flavin adenine dinucleotide oxidized", "charge": 0, "id": "fad_c"}, {"notes": {"original_bigg_ids": ["fdp_c"]}, "compartment": "c", "name": "D-Fructose 1,6-bisphosphate", "charge": 0, "id": "fdp_c"}, {"notes": {"original_bigg_ids": ["fe2_c"]}, "compartment": "c", "name": "Fe2+", "charge": 0, "id": "fe2_c"}, {"notes": {"original_bigg_ids": ["fmn_c"]}, "compartment": "c", "name": "FMN", "charge": 0, "id": "fmn_c"}, {"notes": {"original_bigg_ids": ["for_c"]}, "compartment": "c", "name": "Formate", "charge": 0, "id": "for_c"}, {"notes": {"original_bigg_ids": ["fru_c"]}, "compartment": "c", "name": "D-Fructose", "charge": 0, "id": "fru_c"}, {"notes": {"original_bigg_ids": ["fum_c"]}, "compartment": "c", "name": "Fumarate", "charge": 0, "id": "fum_c"}, {"notes": {"original_bigg_ids": ["g1p_c"]}, "compartment": "c", "name": "D-Glucose 1-phosphate", "charge": 0, "id": "g1p_c"}, {"notes": {"original_bigg_ids": ["g3p_c"]}, "compartment": "c", "name": "Glyceraldehyde 3-phosphate", "charge": 0, "id": "g3p_c"}, {"notes": {"original_bigg_ids": ["g3pc_c"]}, "compartment": "c", "name": "Sn-Glycero-3-phosphocholine", "charge": 0, "id": "g3pc_c"}, {"notes": {"original_bigg_ids": ["g6p_c"]}, "compartment": "c", "name": "D-Glucose 6-phosphate", "charge": 0, "id": "g6p_c"}, {"notes": {"original_bigg_ids": ["gal_c"]}, "compartment": "c", "name": "D-Galactose", "charge": 0, "id": "gal_c"}, {"notes": {"original_bigg_ids": ["gal1p_c"]}, "compartment": "c", "name": "Alpha-D-Galactose 1-phosphate", "charge": 0, "id": "gal1p_c"}, {"notes": {"original_bigg_ids": ["galt_c"]}, "compartment": "c", "name": "Galactitol", "charge": 0, "id": "galt_c"}, {"notes": {"original_bigg_ids": ["gam_c"]}, "compartment": "c", "name": "D-Glucosamine", "charge": 0, "id": "gam_c"}, {"notes": {"original_bigg_ids": ["gam6p_c"]}, "compartment": "c", "name": "D-Glucosamine 6-phosphate", "charge": 0, "id": "gam6p_c"}, {"notes": {"original_bigg_ids": ["gdp_c"]}, "compartment": "c", "name": "GDP", "charge": 0, "id": "gdp_c"}, {"notes": {"original_bigg_ids": ["glc_DASH_D_c"]}, "compartment": "c", "name": "D-Glucose", "charge": 0, "id": "glc__D_c"}, {"notes": {"original_bigg_ids": ["glcur_c"]}, "compartment": "c", "name": "D-Glucuronate", "charge": 0, "id": "glcur_c"}, {"notes": {"original_bigg_ids": ["gln_DASH_L_c"]}, "compartment": "c", "name": "L-Glutamine", "charge": 0, "id": "gln__L_c"}, {"notes": {"original_bigg_ids": ["glu_DASH_L_c"]}, "compartment": "c", "name": "L-Glutamate", "charge": 0, "id": "glu__L_c"}, {"notes": {"original_bigg_ids": ["glucys_c"]}, "compartment": "c", "name": "Gamma-L-Glutamyl-L-cysteine", "charge": 0, "id": "glucys_c"}, {"notes": {"original_bigg_ids": ["gly_c"]}, "compartment": "c", "name": "Glycine", "charge": 0, "id": "gly_c"}, {"notes": {"original_bigg_ids": ["glyc_c"]}, "compartment": "c", "name": "Glycerol", "charge": 0, "id": "glyc_c"}, {"notes": {"original_bigg_ids": ["glyc3p_c"]}, "compartment": "c", "name": "Glycerol 3-phosphate", "charge": 0, "id": "glyc3p_c"}, {"notes": {"original_bigg_ids": ["gmp_c"]}, "compartment": "c", "name": "GMP", "charge": 0, "id": "gmp_c"}, {"notes": {"original_bigg_ids": ["gsn_c"]}, "compartment": "c", "name": "Guanosine", "charge": 0, "id": "gsn_c"}, {"notes": {"original_bigg_ids": ["gthox_c"]}, "compartment": "c", "name": "Oxidized glutathione", "charge": 0, "id": "gthox_c"}, {"notes": {"original_bigg_ids": ["gthrd_c"]}, "compartment": "c", "name": "Reduced glutathione", "charge": 0, "id": "gthrd_c"}, {"notes": {"original_bigg_ids": ["gtp_c"]}, "compartment": "c", "name": "GTP", "charge": 0, "id": "gtp_c"}, {"notes": {"original_bigg_ids": ["gua_c"]}, "compartment": "c", "name": "Guanine", "charge": 0, "id": "gua_c"}, {"notes": {"original_bigg_ids": ["guln_c"]}, "compartment": "c", "name": "Guln c", "charge": 0, "id": "guln_c"}, {"notes": {"original_bigg_ids": ["h_c"]}, "compartment": "c", "name": "H+", "charge": 0, "id": "h_c"}, {"notes": {"original_bigg_ids": ["h2o_c"]}, "compartment": "c", "name": "H2O", "charge": 0, "id": "h2o_c"}, {"notes": {"original_bigg_ids": ["h2o2_c"]}, "compartment": "c", "name": "Hydrogen peroxide", "charge": 0, "id": "h2o2_c"}, {"notes": {"original_bigg_ids": ["hco3_c"]}, "compartment": "c", "name": "Bicarbonate", "charge": 0, "id": "hco3_c"}, {"notes": {"original_bigg_ids": ["hcys_DASH_L_c"]}, "compartment": "c", "name": "L-Homocysteine", "charge": 0, "id": "hcys__L_c"}, {"notes": {"original_bigg_ids": ["hdca_c"]}, "compartment": "c", "name": "Hexadecanoate (n-C16:0)", "charge": 0, "id": "hdca_c"}, {"notes": {"original_bigg_ids": ["hmbil_c"]}, "compartment": "c", "name": "Hydroxymethylbilane", "charge": 0, "id": "hmbil_c"}, {"notes": {"original_bigg_ids": ["hxan_c"]}, "compartment": "c", "name": "Hypoxanthine", "charge": 0, "id": "hxan_c"}, {"notes": {"original_bigg_ids": ["icit_c"]}, "compartment": "c", "name": "Isocitrate", "charge": 0, "id": "icit_c"}, {"notes": {"original_bigg_ids": ["imp_c"]}, "compartment": "c", "name": "IMP", "charge": 0, "id": "imp_c"}, {"notes": {"original_bigg_ids": ["inost_c"]}, "compartment": "c", "name": "Myo-Inositol", "charge": 0, "id": "inost_c"}, {"notes": {"original_bigg_ids": ["ins_c"]}, "compartment": "c", "name": "Inosine", "charge": 0, "id": "ins_c"}, {"notes": {"original_bigg_ids": ["k_c"]}, "compartment": "c", "name": "Potassium", "charge": 0, "id": "k_c"}, {"notes": {"original_bigg_ids": ["lac_DASH_D_c"]}, "compartment": "c", "name": "D-Lactate", "charge": 0, "id": "lac__D_c"}, {"notes": {"original_bigg_ids": ["lac_DASH_L_c"]}, "compartment": "c", "name": "L-Lactate", "charge": 0, "id": "lac__L_c"}, {"notes": {"original_bigg_ids": ["leuktrA4_c"]}, "compartment": "c", "name": "LeuktrA4 c", "charge": 0, "id": "leuktrA4_c"}, {"notes": {"original_bigg_ids": ["leuktrB4_c"]}, "compartment": "c", "name": "LeuktrB4 c", "charge": 0, "id": "leuktrB4_c"}, {"notes": {"original_bigg_ids": ["lgt_DASH_S_c"]}, "compartment": "c", "name": "(R)-S-Lactoylglutathione", "charge": 0, "id": "lgt__S_c"}, {"notes": {"original_bigg_ids": ["lnlc_c"]}, "compartment": "c", "name": "Lnlc c", "charge": 0, "id": "lnlc_c"}, {"notes": {"original_bigg_ids": ["lnlccoa_c"]}, "compartment": "c", "name": "Lnlccoa c", "charge": 0, "id": "lnlccoa_c"}, {"notes": {"original_bigg_ids": ["lnlccrn_c"]}, "compartment": "c", "name": "Lnlccrn c", "charge": 0, "id": "lnlccrn_c"}, {"notes": {"original_bigg_ids": ["lpchol_hs_16_0_c"]}, "compartment": "c", "name": "Lysophosphatidylcholine (homo sapiens, C16:0) cytosol", "charge": 0, "id": "lpchol_hs_16_0_c"}, {"notes": {"original_bigg_ids": ["lpchol_hs_18_1_c"]}, "compartment": "c", "name": "Lpchol hs 18 1[c]", "charge": 0, "id": "lpchol_hs_18_1_c"}, {"notes": {"original_bigg_ids": ["lpchol_hs_18_2_c"]}, "compartment": "c", "name": "Lpchol hs 18 2[c]", "charge": 0, "id": "lpchol_hs_18_2_c"}, {"notes": {"original_bigg_ids": ["mal_DASH_L_c"]}, "compartment": "c", "name": "L-Malate", "charge": 0, "id": "mal__L_c"}, {"notes": {"original_bigg_ids": ["man_c"]}, "compartment": "c", "name": "D-Mannose", "charge": 0, "id": "man_c"}, {"notes": {"original_bigg_ids": ["man1p_c"]}, "compartment": "c", "name": "D-Mannose 1-phosphate", "charge": 0, "id": "man1p_c"}, {"notes": {"original_bigg_ids": ["man6p_c"]}, "compartment": "c", "name": "D-Mannose 6-phosphate", "charge": 0, "id": "man6p_c"}, {"notes": {"original_bigg_ids": ["mepi_c"]}, "compartment": "c", "name": "Mepi c", "charge": 0, "id": "mepi_c"}, {"notes": {"original_bigg_ids": ["met_DASH_L_c"]}, "compartment": "c", "name": "L-Methionine", "charge": 0, "id": "met__L_c"}, {"notes": {"original_bigg_ids": ["mi1345p_c"]}, "compartment": "c", "name": "1D myo Inositol 1 3 4 5 tetrakisphosphate C6H8O18P4", "charge": 0, "id": "mi1345p_c"}, {"notes": {"original_bigg_ids": ["mi134p_c"]}, "compartment": "c", "name": "Mi134p c", "charge": 0, "id": "mi134p_c"}, {"notes": {"original_bigg_ids": ["mi145p_c"]}, "compartment": "c", "name": "1D myo Inositol 1 4 5 trisphosphate C6H9O15P3", "charge": 0, "id": "mi145p_c"}, {"notes": {"original_bigg_ids": ["mi14p_c"]}, "compartment": "c", "name": "Mi14p c", "charge": 0, "id": "mi14p_c"}, {"notes": {"original_bigg_ids": ["mi1p_DASH_D_c"]}, "compartment": "c", "name": "1D-myo-Inositol 1-phosphate", "charge": 0, "id": "mi1p__D_c"}, {"notes": {"original_bigg_ids": ["mthgxl_c"]}, "compartment": "c", "name": "Methylglyoxal", "charge": 0, "id": "mthgxl_c"}, {"notes": {"original_bigg_ids": ["na1_c"]}, "compartment": "c", "name": "Sodium", "charge": 0, "id": "na1_c"}, {"notes": {"original_bigg_ids": ["nac_c"]}, "compartment": "c", "name": "Nicotinate", "charge": 0, "id": "nac_c"}, {"notes": {"original_bigg_ids": ["nad_c"]}, "compartment": "c", "name": "Nicotinamide adenine dinucleotide", "charge": 0, "id": "nad_c"}, {"notes": {"original_bigg_ids": ["nadh_c"]}, "compartment": "c", "name": "Nicotinamide adenine dinucleotide - reduced", "charge": 0, "id": "nadh_c"}, {"notes": {"original_bigg_ids": ["nadp_c"]}, "compartment": "c", "name": "Nicotinamide adenine dinucleotide phosphate", "charge": 0, "id": "nadp_c"}, {"notes": {"original_bigg_ids": ["nadph_c"]}, "compartment": "c", "name": "Nicotinamide adenine dinucleotide phosphate - reduced", "charge": 0, "id": "nadph_c"}, {"notes": {"original_bigg_ids": ["ncam_c"]}, "compartment": "c", "name": "Nicotinamide", "charge": 0, "id": "ncam_c"}, {"notes": {"original_bigg_ids": ["nh4_c"]}, "compartment": "c", "name": "Ammonium", "charge": 0, "id": "nh4_c"}, {"notes": {"original_bigg_ids": ["nicrns_c"]}, "compartment": "c", "name": "Nicotinate D-ribonucleoside", "charge": 0, "id": "nicrns_c"}, {"notes": {"original_bigg_ids": ["nicrnt_c"]}, "compartment": "c", "name": "Nicotinate D-ribonucleotide", "charge": 0, "id": "nicrnt_c"}, {"notes": {"original_bigg_ids": ["nmn_c"]}, "compartment": "c", "name": "NMN", "charge": 0, "id": "nmn_c"}, {"notes": {"original_bigg_ids": ["normete_DASH_L_c"]}, "compartment": "c", "name": "Normete  L c", "charge": 0, "id": "normete__L_c"}, {"notes": {"original_bigg_ids": ["nrpphr_c"]}, "compartment": "c", "name": "Nrpphr c", "charge": 0, "id": "nrpphr_c"}, {"notes": {"original_bigg_ids": ["o2_c"]}, "compartment": "c", "name": "O2", "charge": 0, "id": "o2_c"}, {"notes": {"original_bigg_ids": ["oaa_c"]}, "compartment": "c", "name": "Oxaloacetate", "charge": 0, "id": "oaa_c"}, {"notes": {"original_bigg_ids": ["ocdcea_c"]}, "compartment": "c", "name": "Octadecenoate (n-C18:1)", "charge": 0, "id": "ocdcea_c"}, {"notes": {"original_bigg_ids": ["odecoa_c"]}, "compartment": "c", "name": "Octadecenoyl-CoA (n-C18:1CoA)", "charge": 0, "id": "odecoa_c"}, {"notes": {"original_bigg_ids": ["odecrn_c"]}, "compartment": "c", "name": "Odecrn c", "charge": 0, "id": "odecrn_c"}, {"notes": {"original_bigg_ids": ["orn_c"]}, "compartment": "c", "name": "Ornithine", "charge": 0, "id": "orn_c"}, {"notes": {"original_bigg_ids": ["orot_c"]}, "compartment": "c", "name": "Orotate", "charge": 0, "id": "orot_c"}, {"notes": {"original_bigg_ids": ["orot5p_c"]}, "compartment": "c", "name": "Orotidine 5'-phosphate", "charge": 0, "id": "orot5p_c"}, {"notes": {"original_bigg_ids": ["pa_hs_16_0_16_0_c"]}, "compartment": "c", "name": "Pa hs 16 0 16 0[c]", "charge": 0, "id": "pa_hs_16_0_16_0_c"}, {"notes": {"original_bigg_ids": ["pa_hs_16_0_18_1_c"]}, "compartment": "c", "name": "Pa hs 16 0 18 1[c]", "charge": 0, "id": "pa_hs_16_0_18_1_c"}, {"notes": {"original_bigg_ids": ["pa_hs_16_0_18_2_c"]}, "compartment": "c", "name": "Pa hs 16 0 18 2[c]", "charge": 0, "id": "pa_hs_16_0_18_2_c"}, {"notes": {"original_bigg_ids": ["pa_hs_18_1_18_1_c"]}, "compartment": "c", "name": "Pa hs 18 1 18 1[c]", "charge": 0, "id": "pa_hs_18_1_18_1_c"}, {"notes": {"original_bigg_ids": ["pa_hs_18_1_18_2_c"]}, "compartment": "c", "name": "Pa hs 18 1 18 2[c]", "charge": 0, "id": "pa_hs_18_1_18_2_c"}, {"notes": {"original_bigg_ids": ["pa_hs_18_2_16_0_c"]}, "compartment": "c", "name": "Phosphatidic acid (homo sapiens, C18:2, C16:0)", "charge": 0, "id": "pa_hs_18_2_16_0_c"}, {"notes": {"original_bigg_ids": ["pa_hs_18_2_18_1_c"]}, "compartment": "c", "name": "Phosphatidic acid (homo sapiens, C18:2, C18:1)", "charge": 0, "id": "pa_hs_18_2_18_1_c"}, {"notes": {"original_bigg_ids": ["pail45p_hs_16_0_16_0_c"]}, "compartment": "c", "name": "Pail45p hs 16 0 16 0[c]", "charge": 0, "id": "pail45p_hs_16_0_16_0_c"}, {"notes": {"original_bigg_ids": ["pail45p_hs_16_0_18_1_c"]}, "compartment": "c", "name": "Pail45p hs 16 0 18 1[c]", "charge": 0, "id": "pail45p_hs_16_0_18_1_c"}, {"notes": {"original_bigg_ids": ["pail45p_hs_16_0_18_2_c"]}, "compartment": "c", "name": "Pail45p hs 16 0 18 2[c]", "charge": 0, "id": "pail45p_hs_16_0_18_2_c"}, {"notes": {"original_bigg_ids": ["pail45p_hs_18_1_18_1_c"]}, "compartment": "c", "name": "Pail45p hs 18 1 18 1[c]", "charge": 0, "id": "pail45p_hs_18_1_18_1_c"}, {"notes": {"original_bigg_ids": ["pail45p_hs_18_1_18_2_c"]}, "compartment": "c", "name": "Pail45p hs 18 1 18 2[c]", "charge": 0, "id": "pail45p_hs_18_1_18_2_c"}, {"notes": {"original_bigg_ids": ["pail45p_hs_18_2_16_0_c"]}, "compartment": "c", "name": "Phosphatidylinositol 4,5-bisphosphate (homo sapiens, C18:2, C16:0)", "charge": 0, "id": "pail45p_hs_18_2_16_0_c"}, {"notes": {"original_bigg_ids": ["pail45p_hs_18_2_18_1_c"]}, "compartment": "c", "name": "Phosphatidylinositol 4,5-bisphosphate (homo sapiens, C18:2, C18:1)", "charge": 0, "id": "pail45p_hs_18_2_18_1_c"}, {"notes": {"original_bigg_ids": ["pail4p_hs_16_0_16_0_c"]}, "compartment": "c", "name": "Pail4p hs 16 0 16 0[c]", "charge": 0, "id": "pail4p_hs_16_0_16_0_c"}, {"notes": {"original_bigg_ids": ["pail4p_hs_16_0_18_1_c"]}, "compartment": "c", "name": "Pail4p hs 16 0 18 1[c]", "charge": 0, "id": "pail4p_hs_16_0_18_1_c"}, {"notes": {"original_bigg_ids": ["pail4p_hs_16_0_18_2_c"]}, "compartment": "c", "name": "Pail4p hs 16 0 18 2[c]", "charge": 0, "id": "pail4p_hs_16_0_18_2_c"}, {"notes": {"original_bigg_ids": ["pail4p_hs_18_1_18_1_c"]}, "compartment": "c", "name": "Pail4p hs 18 1 18 1[c]", "charge": 0, "id": "pail4p_hs_18_1_18_1_c"}, {"notes": {"original_bigg_ids": ["pail4p_hs_18_1_18_2_c"]}, "compartment": "c", "name": "Pail4p hs 18 1 18 2[c]", "charge": 0, "id": "pail4p_hs_18_1_18_2_c"}, {"notes": {"original_bigg_ids": ["pail4p_hs_18_2_16_0_c"]}, "compartment": "c", "name": "1-Phosphatidyl-1D-myo-inositol 4-phosphate (homo sapiens, C18:2, C16:0)", "charge": 0, "id": "pail4p_hs_18_2_16_0_c"}, {"notes": {"original_bigg_ids": ["pail4p_hs_18_2_18_1_c"]}, "compartment": "c", "name": "1-Phosphatidyl-1D-myo-inositol 4-phosphate (homo sapiens, C18:2, C18:1)", "charge": 0, "id": "pail4p_hs_18_2_18_1_c"}, {"notes": {"original_bigg_ids": ["pail_hs_16_0_16_0_c"]}, "compartment": "c", "name": "Pail hs 16 0 16 0[c]", "charge": 0, "id": "pail_hs_16_0_16_0_c"}, {"notes": {"original_bigg_ids": ["pail_hs_16_0_18_1_c"]}, "compartment": "c", "name": "Pail hs 16 0 18 1[c]", "charge": 0, "id": "pail_hs_16_0_18_1_c"}, {"notes": {"original_bigg_ids": ["pail_hs_16_0_18_2_c"]}, "compartment": "c", "name": "Pail hs 16 0 18 2[c]", "charge": 0, "id": "pail_hs_16_0_18_2_c"}, {"notes": {"original_bigg_ids": ["pail_hs_18_1_18_1_c"]}, "compartment": "c", "name": "Pail hs 18 1 18 1[c]", "charge": 0, "id": "pail_hs_18_1_18_1_c"}, 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{"original_bigg_ids": ["pe_hs_16_0_18_1_c"]}, "compartment": "c", "name": "Pe hs 16 0 18 1[c]", "charge": 0, "id": "pe_hs_16_0_18_1_c"}, {"notes": {"original_bigg_ids": ["pe_hs_16_0_18_2_c"]}, "compartment": "c", "name": "Pe hs 16 0 18 2[c]", "charge": 0, "id": "pe_hs_16_0_18_2_c"}, {"notes": {"original_bigg_ids": ["pe_hs_18_1_18_1_c"]}, "compartment": "c", "name": "Pe hs 18 1 18 1[c]", "charge": 0, "id": "pe_hs_18_1_18_1_c"}, {"notes": {"original_bigg_ids": ["pe_hs_18_1_18_2_c"]}, "compartment": "c", "name": "Pe hs 18 1 18 2[c]", "charge": 0, "id": "pe_hs_18_1_18_2_c"}, {"notes": {"original_bigg_ids": ["pe_hs_18_2_16_0_c"]}, "compartment": "c", "name": "Phosphatidylethanolamine (homo sapiens, C18:2, C16:0)", "charge": 0, "id": "pe_hs_18_2_16_0_c"}, {"notes": {"original_bigg_ids": ["pe_hs_18_2_18_1_c"]}, "compartment": "c", "name": "Phosphatidylethanolamine (homo sapiens, C18:2, C18:1)", "charge": 0, "id": "pe_hs_18_2_18_1_c"}, {"notes": {"original_bigg_ids": ["pep_c"]}, "compartment": "c", "name": "Phosphoenolpyruvate", "charge": 0, "id": "pep_c"}, {"notes": {"original_bigg_ids": ["phe_DASH_L_c"]}, "compartment": "c", "name": "L-Phenylalanine", "charge": 0, "id": "phe__L_c"}, {"notes": {"original_bigg_ids": ["pheme_c"]}, "compartment": "c", "name": "Protoheme", "charge": 0, "id": "pheme_c"}, {"notes": {"original_bigg_ids": ["phpyr_c"]}, "compartment": "c", "name": "Phenylpyruvate", "charge": 0, "id": "phpyr_c"}, {"notes": {"original_bigg_ids": ["pi_c"]}, "compartment": "c", "name": "Phosphate", "charge": 0, "id": "pi_c"}, {"notes": {"original_bigg_ids": ["pmtcoa_c"]}, "compartment": "c", "name": "Palmitoyl-CoA (n-C16:0CoA)", "charge": 0, "id": "pmtcoa_c"}, {"notes": {"original_bigg_ids": ["pmtcrn_c"]}, "compartment": "c", "name": "Pmtcrn c", "charge": 0, "id": "pmtcrn_c"}, {"notes": {"original_bigg_ids": ["ppbng_c"]}, "compartment": "c", "name": "Porphobilinogen", "charge": 0, "id": "ppbng_c"}, {"notes": {"original_bigg_ids": ["ppi_c"]}, "compartment": "c", "name": "Diphosphate", "charge": 0, "id": "ppi_c"}, {"notes": {"original_bigg_ids": ["ppp9_c"]}, "compartment": "c", "name": "Protoporphyrin", "charge": 0, "id": "ppp9_c"}, {"notes": {"original_bigg_ids": ["pppg9_c"]}, "compartment": "c", "name": "Protoporphyrinogen IX", "charge": 0, "id": "pppg9_c"}, {"notes": {"original_bigg_ids": ["prpp_c"]}, "compartment": "c", "name": "5-Phospho-alpha-D-ribose 1-diphosphate", "charge": 0, "id": "prpp_c"}, {"notes": {"original_bigg_ids": ["ptrc_c"]}, "compartment": "c", "name": "Putrescine", "charge": 0, "id": "ptrc_c"}, {"notes": {"original_bigg_ids": ["pyam5p_c"]}, "compartment": "c", "name": "Pyridoxamine 5'-phosphate", "charge": 0, "id": "pyam5p_c"}, {"notes": {"original_bigg_ids": ["pydam_c"]}, "compartment": "c", "name": "Pyridoxamine", "charge": 0, "id": "pydam_c"}, {"notes": {"original_bigg_ids": ["pydx_c"]}, "compartment": "c", "name": "Pyridoxal", "charge": 0, "id": "pydx_c"}, {"notes": {"original_bigg_ids": ["pydx5p_c"]}, "compartment": "c", "name": "Pyridoxal 5'-phosphate", "charge": 0, "id": "pydx5p_c"}, {"notes": {"original_bigg_ids": ["pydxn_c"]}, "compartment": "c", "name": "Pyridoxine", "charge": 0, "id": "pydxn_c"}, {"notes": {"original_bigg_ids": ["pyr_c"]}, "compartment": "c", "name": "Pyruvate", "charge": 0, "id": "pyr_c"}, {"notes": {"original_bigg_ids": ["r1p_c"]}, "compartment": "c", "name": "Alpha-D-Ribose 1-phosphate", "charge": 0, "id": "r1p_c"}, {"notes": {"original_bigg_ids": ["r5p_c"]}, "compartment": "c", "name": "Alpha-D-Ribose 5-phosphate", "charge": 0, "id": "r5p_c"}, {"notes": {"original_bigg_ids": ["ribflv_c"]}, "compartment": "c", "name": "Riboflavin", "charge": 0, "id": "ribflv_c"}, {"notes": {"original_bigg_ids": ["rnam_c"]}, "compartment": "c", "name": "N Ribosylnicotinamide C11H15N2O5", "charge": 0, "id": "rnam_c"}, {"notes": {"original_bigg_ids": ["ru5p_DASH_D_c"]}, "compartment": "c", "name": "D-Ribulose 5-phosphate", "charge": 0, "id": "ru5p__D_c"}, {"notes": {"original_bigg_ids": ["s7p_c"]}, "compartment": "c", "name": "Sedoheptulose 7-phosphate", "charge": 0, "id": "s7p_c"}, {"notes": {"original_bigg_ids": ["sbt_DASH_D_c"]}, "compartment": "c", "name": "D-Sorbitol", "charge": 0, "id": "sbt__D_c"}, {"notes": {"original_bigg_ids": ["spmd_c"]}, "compartment": "c", "name": "Spermidine", "charge": 0, "id": "spmd_c"}, {"notes": {"original_bigg_ids": ["sprm_c"]}, "compartment": "c", "name": "Spermine C10H30N4", "charge": 0, "id": "sprm_c"}, {"notes": {"original_bigg_ids": ["thm_c"]}, "compartment": "c", "name": "Thiamin", "charge": 0, "id": "thm_c"}, {"notes": {"original_bigg_ids": ["thmmp_c"]}, "compartment": "c", "name": "Thiamin monophosphate", "charge": 0, "id": "thmmp_c"}, {"notes": {"original_bigg_ids": ["thmpp_c"]}, "compartment": "c", "name": "Thiamine diphosphate", "charge": 0, "id": "thmpp_c"}, {"notes": {"original_bigg_ids": ["thmtp_c"]}, "compartment": "c", "name": "Thiamin triphosphate C12H16N4O10P3S", "charge": 0, "id": "thmtp_c"}, {"notes": {"original_bigg_ids": ["udp_c"]}, "compartment": "c", "name": "UDP", "charge": 0, "id": "udp_c"}, {"notes": {"original_bigg_ids": ["udpg_c"]}, "compartment": "c", "name": "UDPglucose", "charge": 0, "id": "udpg_c"}, {"notes": {"original_bigg_ids": ["udpgal_c"]}, "compartment": "c", "name": "UDPgalactose", "charge": 0, "id": "udpgal_c"}, {"notes": {"original_bigg_ids": ["udpglcur_c"]}, "compartment": "c", "name": "UDP-D-glucuronate", "charge": 0, "id": "udpglcur_c"}, {"notes": {"original_bigg_ids": ["ump_c"]}, "compartment": "c", "name": "UMP", "charge": 0, "id": "ump_c"}, {"notes": {"original_bigg_ids": ["uppg3_c"]}, "compartment": "c", "name": "Uroporphyrinogen III", "charge": 0, "id": "uppg3_c"}, {"notes": {"original_bigg_ids": ["urea_c"]}, "compartment": "c", "name": "Urea", "charge": 0, "id": "urea_c"}, {"notes": {"original_bigg_ids": ["uri_c"]}, "compartment": "c", "name": "Uridine", "charge": 0, "id": "uri_c"}, {"notes": {"original_bigg_ids": ["utp_c"]}, "compartment": "c", "name": "UTP", "charge": 0, "id": "utp_c"}, {"notes": {"original_bigg_ids": ["xmp_c"]}, "compartment": "c", "name": "Xanthosine 5'-phosphate", "charge": 0, "id": "xmp_c"}, {"notes": {"original_bigg_ids": ["xu5p_DASH_D_c"]}, "compartment": "c", "name": "D-Xylulose 5-phosphate", "charge": 0, "id": "xu5p__D_c"}, {"notes": {"original_bigg_ids": ["xylt_c"]}, "compartment": "c", "name": "Xylitol C5H12O5", "charge": 0, "id": "xylt_c"}, {"notes": {"original_bigg_ids": ["xylu_DASH_D_c"]}, "compartment": "c", "name": "D-Xylulose", "charge": 0, "id": "xylu__D_c"}, {"notes": {"original_bigg_ids": ["xylu_DASH_L_c"]}, "compartment": "c", "name": "L-Xylulose", "charge": 0, "id": "xylu__L_c"}, {"notes": {"original_bigg_ids": ["35cgmp_e"]}, "compartment": "e", "name": "3',5'-Cyclic GMP", "charge": 0, "id": "35cgmp_e"}, {"notes": {"original_bigg_ids": ["3moxtyr_e"]}, "compartment": "e", "name": "3moxtyr c", "charge": 0, "id": "3moxtyr_e"}, {"notes": {"original_bigg_ids": ["4pyrdx_e"]}, "compartment": "e", "name": "4pyrdx c", "charge": 0, "id": "4pyrdx_e"}, {"notes": {"original_bigg_ids": ["5aop_e"]}, "compartment": "e", "name": "5-Amino-4-oxopentanoate", "charge": 0, "id": "5aop_e"}, {"notes": {"original_bigg_ids": ["ac_e"]}, "compartment": "e", "name": "Acetate", "charge": 0, "id": "ac_e"}, {"notes": {"original_bigg_ids": ["acald_e"]}, "compartment": "e", "name": "Acetaldehyde", "charge": 0, "id": "acald_e"}, {"notes": {"original_bigg_ids": ["acnam_e"]}, "compartment": "e", "name": "N-Acetylneuraminate", "charge": 0, "id": "acnam_e"}, {"notes": {"original_bigg_ids": ["ade_e"]}, "compartment": "e", "name": "Adenine", "charge": 0, "id": "ade_e"}, {"notes": {"original_bigg_ids": ["adn_e"]}, "compartment": "e", "name": "Adenosine", "charge": 0, "id": "adn_e"}, {"notes": {"original_bigg_ids": ["adrnl_e"]}, "compartment": "e", "name": "Adrnl c", "charge": 0, "id": "adrnl_e"}, {"notes": {"original_bigg_ids": ["ala_DASH_L_e"]}, "compartment": "e", "name": "L-Alanine", "charge": 0, "id": "ala__L_e"}, {"notes": {"original_bigg_ids": ["arg_DASH_L_e"]}, "compartment": "e", "name": "L-Arginine", "charge": 0, "id": "arg__L_e"}, {"notes": {"original_bigg_ids": ["ascb_DASH_L_e"]}, "compartment": "e", "name": "L-Ascorbate", "charge": 0, "id": "ascb__L_e"}, {"notes": {"original_bigg_ids": ["bilglcur_e"]}, "compartment": "e", "name": "Bilglcur c", "charge": 0, "id": "bilglcur_e"}, {"notes": {"original_bigg_ids": ["ca2_e"]}, "compartment": "e", "name": "Calcium", "charge": 0, "id": "ca2_e"}, {"notes": {"original_bigg_ids": ["camp_e"]}, "compartment": "e", "name": "CAMP", "charge": 0, "id": "camp_e"}, {"notes": {"original_bigg_ids": ["chol_e"]}, "compartment": "e", "name": "Choline", "charge": 0, "id": "chol_e"}, {"notes": {"original_bigg_ids": ["cl_e"]}, "compartment": "e", "name": "Chloride", "charge": 0, "id": "cl_e"}, {"notes": {"original_bigg_ids": ["co_e"]}, "compartment": "e", "name": "Carbon monoxide", "charge": 0, "id": "co_e"}, {"notes": {"original_bigg_ids": ["co2_e"]}, "compartment": "e", "name": "CO2", "charge": 0, "id": "co2_e"}, {"notes": {"original_bigg_ids": ["cys_DASH_L_e"]}, "compartment": "e", "name": "L-Cysteine", "charge": 0, "id": "cys__L_e"}, {"notes": {"original_bigg_ids": ["dhdascb_e"]}, "compartment": "e", "name": "Dhdascb c", "charge": 0, "id": "dhdascb_e"}, {"notes": {"original_bigg_ids": ["dopa_e"]}, "compartment": "e", "name": "Dopamine", "charge": 0, "id": "dopa_e"}, {"notes": {"original_bigg_ids": ["etha_e"]}, "compartment": "e", "name": "Ethanolamine", "charge": 0, "id": "etha_e"}, {"notes": {"original_bigg_ids": ["fe2_e"]}, "compartment": "e", "name": "Fe2+", "charge": 0, "id": "fe2_e"}, {"notes": {"original_bigg_ids": ["fru_e"]}, "compartment": "e", "name": "D-Fructose", "charge": 0, "id": "fru_e"}, {"notes": {"original_bigg_ids": ["fum_e"]}, "compartment": "e", "name": "Fumarate", "charge": 0, "id": "fum_e"}, {"notes": {"original_bigg_ids": ["gal_e"]}, "compartment": "e", "name": "D-Galactose", "charge": 0, "id": "gal_e"}, {"notes": {"original_bigg_ids": ["gam_e"]}, "compartment": "e", "name": "D-Glucosamine", "charge": 0, "id": "gam_e"}, {"notes": {"original_bigg_ids": ["glc_DASH_D_e"]}, "compartment": "e", "name": "D-Glucose", "charge": 0, "id": "glc__D_e"}, {"notes": {"original_bigg_ids": ["gln_DASH_L_e"]}, "compartment": "e", "name": "L-Glutamine", "charge": 0, "id": "gln__L_e"}, {"notes": {"original_bigg_ids": ["gluala_e"]}, "compartment": "e", "name": "5 L Glutamyl L alanine C8H13N2O5", "charge": 0, "id": "gluala_e"}, {"notes": {"original_bigg_ids": ["gly_e"]}, "compartment": "e", "name": "Glycine", "charge": 0, "id": "gly_e"}, {"notes": {"original_bigg_ids": ["glyc_e"]}, "compartment": "e", "name": "Glycerol", "charge": 0, "id": "glyc_e"}, {"notes": {"original_bigg_ids": ["gthox_e"]}, "compartment": "e", "name": "Oxidized glutathione", "charge": 0, "id": "gthox_e"}, {"notes": {"original_bigg_ids": ["h_e"]}, "compartment": "e", "name": "H+", "charge": 0, "id": "h_e"}, {"notes": {"original_bigg_ids": ["h2o_e"]}, "compartment": "e", "name": "H2O", "charge": 0, "id": "h2o_e"}, {"notes": {"original_bigg_ids": ["h2o2_e"]}, "compartment": "e", "name": "Hydrogen peroxide", "charge": 0, "id": "h2o2_e"}, {"notes": {"original_bigg_ids": ["hco3_e"]}, "compartment": "e", "name": "Bicarbonate", "charge": 0, "id": "hco3_e"}, {"notes": {"original_bigg_ids": ["hcys_DASH_L_e"]}, "compartment": "e", "name": "L-Homocysteine", "charge": 0, "id": "hcys__L_e"}, {"notes": {"original_bigg_ids": ["hdca_e"]}, "compartment": "e", "name": "Hexadecanoate (n-C16:0)", "charge": 0, "id": "hdca_e"}, {"notes": {"original_bigg_ids": ["hxan_e"]}, "compartment": "e", "name": "Hypoxanthine", "charge": 0, "id": "hxan_e"}, {"notes": {"original_bigg_ids": ["ins_e"]}, "compartment": "e", "name": "Inosine", "charge": 0, "id": "ins_e"}, {"notes": {"original_bigg_ids": ["k_e"]}, "compartment": "e", "name": "Potassium", "charge": 0, "id": "k_e"}, {"notes": {"original_bigg_ids": ["lac_DASH_D_e"]}, "compartment": "e", "name": "D-Lactate", "charge": 0, "id": "lac__D_e"}, {"notes": {"original_bigg_ids": ["lac_DASH_L_e"]}, "compartment": "e", "name": "L-Lactate", "charge": 0, "id": "lac__L_e"}, {"notes": {"original_bigg_ids": ["leuktrA4_e"]}, "compartment": "e", "name": "LeuktrA4 c", "charge": 0, "id": "leuktrA4_e"}, {"notes": {"original_bigg_ids": ["leuktrB4_e"]}, "compartment": "e", "name": "LeuktrB4 c", "charge": 0, "id": "leuktrB4_e"}, {"notes": {"original_bigg_ids": ["lnlc_e"]}, "compartment": "e", "name": "Lnlc c", "charge": 0, "id": "lnlc_e"}, {"notes": {"original_bigg_ids": ["mal_DASH_L_e"]}, "compartment": "e", "name": "L-Malate", "charge": 0, "id": "mal__L_e"}, {"notes": {"original_bigg_ids": ["man_e"]}, "compartment": "e", "name": "D-Mannose", "charge": 0, "id": "man_e"}, {"notes": {"original_bigg_ids": ["mepi_e"]}, "compartment": "e", "name": "Mepi c", "charge": 0, "id": "mepi_e"}, {"notes": {"original_bigg_ids": ["met_DASH_L_e"]}, "compartment": "e", "name": 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{"notes": {"original_bigg_ids": ["orot_e"]}, "compartment": "e", "name": "Orotate", "charge": 0, "id": "orot_e"}, {"notes": {"original_bigg_ids": ["phe_DASH_L_e"]}, "compartment": "e", "name": "L-Phenylalanine", "charge": 0, "id": "phe__L_e"}, {"notes": {"original_bigg_ids": ["pi_e"]}, "compartment": "e", "name": "Phosphate", "charge": 0, "id": "pi_e"}, {"notes": {"original_bigg_ids": ["ptrc_e"]}, "compartment": "e", "name": "Putrescine", "charge": 0, "id": "ptrc_e"}, {"notes": {"original_bigg_ids": ["pydam_e"]}, "compartment": "e", "name": "Pyridoxamine", "charge": 0, "id": "pydam_e"}, {"notes": {"original_bigg_ids": ["pydx_e"]}, "compartment": "e", "name": "Pyridoxal", "charge": 0, "id": "pydx_e"}, {"notes": {"original_bigg_ids": ["pydxn_e"]}, "compartment": "e", "name": "Pyridoxine", "charge": 0, "id": "pydxn_e"}, {"notes": {"original_bigg_ids": ["pyr_e"]}, "compartment": "e", "name": "Pyruvate", "charge": 0, "id": "pyr_e"}, {"notes": {"original_bigg_ids": ["ribflv_e"]}, "compartment": "e", "name": "Riboflavin", "charge": 0, "id": "ribflv_e"}, {"notes": {"original_bigg_ids": ["spmd_e"]}, "compartment": "e", "name": "Spermidine", "charge": 0, "id": "spmd_e"}, {"notes": {"original_bigg_ids": ["sprm_e"]}, "compartment": "e", "name": "Spermine C10H30N4", "charge": 0, "id": "sprm_e"}, {"notes": {"original_bigg_ids": ["thm_e"]}, "compartment": "e", "name": "Thiamin", "charge": 0, "id": "thm_e"}, {"notes": {"original_bigg_ids": ["thmmp_e"]}, "compartment": "e", "name": "Thiamin monophosphate", "charge": 0, "id": "thmmp_e"}, {"notes": {"original_bigg_ids": ["urea_e"]}, "compartment": "e", "name": "Urea", "charge": 0, "id": "urea_e"}, {"notes": {"original_bigg_ids": ["uri_e"]}, "compartment": "e", "name": "Uridine", "charge": 0, "id": "uri_e"}], "version": 1, "id": "iAB_RBC_283"}